742106-23-6Relevant articles and documents
Indolylarylsulfones bearing phenylboronic acid and phenylboronate ester functionalities as potent HIV?1 non-nucleoside reverse transcriptase inhibitors
Xu, Shujing,Song, Shu,Sun, Lin,Gao, Ping,Gao, Shenghua,Ma, Yue,Kang, Dongwei,Cheng, Yusen,Zhang, Xujie,Cherukupalli, Srinivasulu,De Clercq, Erik,Pannecouque, Christophe,Liu, Xinyong,Zhan, Peng
, (2021/12/10)
To explore the chemical space around the entrance channel of the HIV-1 reverse transcriptase (RT) binding pocket, we innovatively designed and synthesized a series of novel indolylarylsulfones (IASs) bearing phenylboronic acid and phenylboronate ester fun
Indole aryl sulfone derivative as well as preparation method and application thereof
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Paragraph 0049-0052, (2021/06/06)
The invention provides an indole aryl sulfone derivative as well as a preparation method and application thereof. The derivative has a structure as shown in a general formula I or II. The invention also relates to a preparation method of the derivative an
Discovery of novel piperidine-substituted indolylarylsulfones as potent HIV NNRTIs via structure-guided scaffold morphing and fragment rearrangement
Li, Xiao,Gao, Ping,Huang, Boshi,Zhou, Zhongxia,Yu, Zhao,Yuan, Zheng,Liu, Huiqing,Pannecouque, Christophe,Daelemans, Dirk,De Clercq, Erik,Zhan, Peng,Liu, Xinyong
, p. 190 - 201 (2016/10/25)
To further explore the chemical space around the entrance channel of HIV-1 reverse transcriptase (RT), a series of novel indolylarylsulfones (IASs) bearing N-substituted piperidine at indole-2-carboxamide were identified as potent HIV NNRTIs by structure-
