74254-53-8

Basic information

• Product Name: dibenzyl ethylmalonate
• Synonyms: dibenzyl ethylmalonate
• CAS NO: 74254-53-8
• Molecular Weight: 312.365
• Mol File: 74254-53-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dibenzyl ethylmalonate(CAS DataBase Reference)
• NIST Chemistry Reference: dibenzyl ethylmalonate(74254-53-8)
• EPA Substance Registry System: dibenzyl ethylmalonate(74254-53-8)

Safety Data

• Hazardous Substances Data: 74254-53-8(Hazardous Substances Data)

Upstream product

• 133-13-1 ethyl diethyl malonate 
• 100-51-6 benzyl alcohol 

Downstream Products

• 15014-25-2 malonic acid dibenzyl ester 
• 42998-51-6 benzyl ethyl malonate 
• 74254-54-9 (-)-(S)-methyl 3,3-bis(benzyloxycarbonyl)-2-methylvalerate 

Relevant articles and documents

Synthesis of the 2-ethyl-3-methylsuccinic acids via a stereospecific malonic ester alkylation

Reaction of (-)-(S)-methyl 2-bromopropionate (4) (obtained from L-alanine) with dibenzyl ethylmalonate gave stereospecifically in four steps (+)-(2R,3S)-2-ethyl-3-methylsuccinic acid (8a) and its diastereoisomer (8b).The malonic ester alkylation proceeded with Walden inversion.The chiroptical properties of the acids and the intermediates are in conformity with the known absolute configurations.