74267-27-9 Usage
Uses
Suitable for intracellular calcium measurements.
General Description
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Purification Methods
Recrystallise it from Me2CO. It forms 1:2 and 1:3 metal/ligand complexes with Mg2+ and Ca2+ ions, respectively, and induces selectivity in membranes for Ca2+ over Mg2+ by a factor of ca 104. [Pretsch et al. Helv Chim Acta 63 191 1980, Simon & Carafoli Methods Enzymol 56 439 1977.]
Check Digit Verification of cas no
The CAS Registry Mumber 74267-27-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,2,6 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 74267-27:
(7*7)+(6*4)+(5*2)+(4*6)+(3*7)+(2*2)+(1*7)=139
139 % 10 = 9
So 74267-27-9 is a valid CAS Registry Number.
InChI:InChI=1/C28H48N2O3/c31-27(29(23-13-5-1-6-14-23)24-15-7-2-8-16-24)21-33-22-28(32)30(25-17-9-3-10-18-25)26-19-11-4-12-20-26/h23-26H,1-22H2
74267-27-9Relevant articles and documents
16. Ionophore vom Typ der 3-Oxapentadiamide
Pretsch, Erno,Ammann, Daniel,Osswald, Hans F.,Guggi, Marc,Simon, Wilhelm
, p. 191 - 196 (1980)
A series of lipophilic 3-oxapentane diamides were prepared and their selectivity in membranes was studied.N,N,N',N'-Tetracyclohexyl-3-oxapentane diamide forms 1:2- and 1:3-metal/ligand-complexes with Mg(2+) and Ca(2+) respectively and induces a selectivity in membranes for Ca(2+) over Mg(2+) by a factor of about 10E4.
