742684-47-5

Upstream product

• 256389-52-3 (R)-2-Allyl-2-(3,4-dimethoxy-phenyl)-malonic acid monomethyl ester 
• 256389-60-3 (S)-2-(3,4-Dimethoxy-phenyl)-2-((E)-2-methoxy-vinyl)-pent-4-enoic acid methyl ester 
• 256389-54-5 (R)-2-(3,4-Dimethoxy-phenyl)-2-hydroxymethyl-pent-4-enoic acid methyl ester 
• 256389-63-6 (S)-2-(3,4-Dimethoxy-phenyl)-2-(2-oxo-ethyl)-pent-4-enoic acid methyl ester 
• 256389-57-8 (R)-2-(3,4-Dimethoxy-phenyl)-2-formyl-pent-4-enoic acid methyl ester 
• 100-46-9 benzylamine 
• 101430-41-5 allyl-(3,4-dimethoxy-phenyl)-malonic acid dimethyl ester 

Downstream Products

• 256389-70-5 (S)-3-Allyl-1-benzyl-3-(3,4-dimethoxy-phenyl)-pyrrolidin-2-one 

Relevant academic research and scientific papers

An easy access to (S)-pyrrolidinones and -pyrrolidines from chiral benzylic malonates

From chiral benzylic malonic acid esters (R)-(+)-4, available with high enantiomeric excesses by enzymatic hydrolysis (PLE acetonic powder), enantiomerically enriched pyrrolidinones 1 and pyrrolidines 2 were prepared. This rapid and competitive method was