742691-96-9Relevant academic research and scientific papers
Construction of azaspirocyclic skeletons mediated by the carbonyl of the Weinreb amide: Formal total synthesis of (±)-cephalotaxine
Ding, Huili,Fan, Yuxue,Jiang, Minghua,Li, Shanshan,Liu, Jianyin,Liu, Lu,Liu, Tianfu,Zhang, Jian
, p. 1879 - 1882 (2022/03/15)
A facile Stevens rearrangement of the Weinreb amide and the subsequent key steps mediated by the carbonyl of the Weinreb amide led to the construction of azaspirocyclic skeletons of some typical alkaloids. And the formal total synthesis of (±)-cephalotaxine was completed via a shorter synthetic route by this efficient method. Further studies on the development and asymmetric synthesis application of this strategy are underway. This journal is
Synthesis of jenamidines A1/A2
Snider, Barry B.,Duvall, Jeremy R.
, p. 4519 - 4522 (2007/10/03)
(Chemical Equation Presented) Addition of the enolate of tert-butyl acetate to cyanamide methyl ester 17 followed by treatment with LHMDS afforded vinylogous urea 19 in 27% yield. Vinylogous urea 19 was also obtained from 37 and tert-butyl cyanoacetate in
