74281-91-7 Usage
Uses
Used in Pharmaceutical Research:
2,3,4,5,6-penta-O-acetyl-1-S-ethyl-1-thio-1-C-(6-thioxo-3,6-dihydro-9H-purin-9-yl)hexitol is used as a research compound for exploring its potential interactions with various biological systems. Its unique structure and functional groups may offer valuable insights for drug development, particularly in the areas of medicinal chemistry and biochemistry.
Used in Drug Development:
In the pharmaceutical industry, 2,3,4,5,6-penta-O-acetyl-1-S-ethyl-1-thio-1-C-(6-thioxo-3,6-dihydro-9H-purin-9-yl)hexitol is used as a lead compound for the development of new drugs. Its complex structure and potential to interact with biological targets make it a promising candidate for the creation of novel therapeutic agents.
Used in Biochemical Studies:
2,3,4,5,6-penta-O-acetyl-1-S-ethyl-1-thio-1-C-(6-thioxo-3,6-dihydro-9H-purin-9-yl)hexitol is utilized as a subject of biochemical research to understand its interactions with enzymes, receptors, and other biomolecules. This knowledge can contribute to the advancement of our understanding of biological processes and the development of targeted therapies.
Note: The specific applications and industries for 2,3,4,5,6-penta-O-acetyl-1-S-ethyl-1-thio-1-C-(6-thioxo-3,6-dihydro-9H-purin-9-yl)hexitol are not explicitly mentioned in the provided materials. The uses listed above are inferred based on the compound's structural complexity and potential for pharmaceutical research and development. Further investigation and research would be required to determine its specific applications and industries.
Check Digit Verification of cas no
The CAS Registry Mumber 74281-91-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,2,8 and 1 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 74281-91:
(7*7)+(6*4)+(5*2)+(4*8)+(3*1)+(2*9)+(1*1)=137
137 % 10 = 7
So 74281-91-7 is a valid CAS Registry Number.
74281-91-7Relevant academic research and scientific papers
ACYCLIC-SUGAR PURINE NUCLEOSIDES DERIVED FROM D-GLUCOSE: STEREOCHEMICAL CORRELATIONS IN ACYCLIC-SUGAR DERIVATIVES UNEQUALLY SUBSTITUTED AT C1
Blieszner, Kathleen C.,Horton, Derek,Markovs, Robert A.
, p. 241 - 262 (2007/10/02)
Condensation of 2,3,4,5,6-penta-O-acetyl-1-bromo-1-S-methyl-1-thio-D-glucitol (1) with 6-chloro-9-(chloromercuri)purine gave 49percent of crystalline, levorotatory (1S)-2,3,4,5,6-penta-O-acetyl-1-(6-chloropurin-9-yl)-1-S-methyl-1-thio-D-glucitol (3), together with a smaller proportion of the syrupy, dextrorotatory (1R) isomer.Thiourea converted 3 into its 6-mercaptopurine analog, whose O-deacetylated derivative could be S-methylated to the corresponding 6-(methylthio)purin-9-yl analog: all compounds in this sequence were crystalline and were the pure (1S) isomers, as were the corresponding 1'-S-ethyl derivatives prepared by a similar route.Crystal-structure analysis of the O-deacetylated derivative of the 1'-S-ethyl analog of 3 established the relative stereochemistry of the ethyltio group, permitting assignment of the (1S) absolute stereochemistry to this compound and thus to all compounds in the sequence starting from 1, including the previously described, crystalline, levorotatory 1-(1,6-dihydro-6-thioxopurin-9-yl)-1-S-ethyl-1-thio-D-glucitol, whose chirality at C-1 had not hitherto been established.The close similarity of the chiroptical properties of the crystalline 1'-S-methyl derivatives to those of their 1'-S-ethyl counterparts permitted firm attribution of (1S) chirality to the former series also.Conformational studies showed that all of the derivatives have the sugar chain in a non-extended (sickle) conformation.
