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Etaqualone, an analog of the hypnotic methaqualone, is a non-barbiturate sedative also known as Quaalude. It is a quinazolone compound with physiological and toxicological properties that have been poorly delineated. Etaqualone is primarily intended for forensic and research applications.

7432-25-9

7432-25-9 Suppliers

This product is a nationally controlled contraband or patented product, and the Lookchem platform doesn't provide relevant sales information.

7432-25-9 Usage

Uses

Used in Forensic Applications:
Etaqualone is used as an analytical reference standard for forensic purposes, aiding in the identification and analysis of substances related to methaqualone and other similar compounds.
Used in Research Applications:
Etaqualone serves as a research tool for studying the effects and mechanisms of non-barbiturate sedatives, particularly in the context of its binding to the beta GABAA receptor and its potential role in negating insomnia.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, etaqualone is marketed as a sedative, hypnotic, muscle relaxant, and central nervous system depressant. It is used as a therapeutic agent for treating insomnia and other related conditions due to its ability to bind to the beta GABAA receptor, which helps alleviate sleep disturbances.

Check Digit Verification of cas no

The CAS Registry Mumber 7432-25-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,3 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7432-25:
(6*7)+(5*4)+(4*3)+(3*2)+(2*2)+(1*5)=89
89 % 10 = 9
So 7432-25-9 is a valid CAS Registry Number.
InChI:InChI=1/C17H16N2O/c1-3-13-8-4-7-11-16(13)19-12(2)18-15-10-6-5-9-14(15)17(19)20/h4-11H,3H2,1-2H3

7432-25-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name etaqualone

1.2 Other means of identification

Product number -
Other names Athinazone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7432-25-9 SDS

7432-25-9Downstream Products

7432-25-9Relevant academic research and scientific papers

Metal-free C-H methylation and acetylation of heteroarenes with PEG-400

Kudale, Vishal Suresh,Wang, Jeh-Jeng

supporting information, p. 3506 - 3511 (2020/06/25)

The generation of a methyl carbon source from renewable and cheap sources is challenging. Herein, we describe a novel and an efficient route for methylation and acetylation of aza-heteroarenes using PEG-400 under O2and TsOH·H2O for the first time by tuning the reaction conditions using a different set of starting materials. The key features of the current protocol are oxidative C-O and C-C bond scission under metal-free conditions with good functional group tolerance, and a broad substrate scope. The potential applicability of the designed methodology was demonstrated for the synthesis of central nervous system (CNS) depressant and anticonvulsant drug molecules by a one-pot strategy.

Synthesis of 3h-quinazolin-4-ones and 4h-3,1-benzoxazin-4-ones via benzylic oxidation and oxidative dehydrogenation using potassium iodide-tert-butyl hydroperoxide

Kumar, R. Arun,Maheswari, C. Uma,Ghantasala, Satheesh,Jyothi,Reddy, K. Rajender

experimental part, p. 401 - 410 (2011/04/18)

A simple and elegant method for benzylic activation was demonstrated employing the potassium iodide/tert-butyl hydrogen peroxide catalytic system. This methodology was further extended for the synthesis of biologically important heterocycles namely, 3H-quinazolin-4-ones and 4H-3,1-benzoxazin-4-ones including mecloqualone and etaqualone which are important quinazolinone-based drugs used for the treatment of insomnia in good yields.