74322-38-6

Basic information

• Product Name: 1-(2-chloro-phenyl)-3-(2-methoxy-phenyl)-thiourea
• CAS NO: 74322-38-6
• Molecular Weight: 292.789
• Mol File: 74322-38-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-chloro-phenyl)-3-(2-methoxy-phenyl)-thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-chloro-phenyl)-3-(2-methoxy-phenyl)-thiourea(74322-38-6)
• EPA Substance Registry System: 1-(2-chloro-phenyl)-3-(2-methoxy-phenyl)-thiourea(74322-38-6)

Safety Data

• Hazardous Substances Data: 74322-38-6(Hazardous Substances Data)

Upstream product

• 2740-81-0 2-chlorophenylisothiocyanate 
• 90-04-0 2-methoxy-phenylamine 

Downstream Products

• 28292-85-5 3-(2-chloro-phenyl)-2-(2-methoxy-phenylimino)-thiazolidin-4-one 
• 76153-62-3 3-(2-Chloro-phenyl)-6-hydroxy-1-(2-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 1843-22-7 N-(2-methoxyphenyl)benzo[d]thiazol-2-amine 
• 76153-45-2 3-(2-Chloro-phenyl)-6-hydroxy-1-(2-methoxy-phenyl)-5-(2-methoxy-phenylazo)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 76153-52-1 3-(2-Chloro-phenyl)-6-hydroxy-1-(2-methoxy-phenyl)-5-(4-methoxy-phenylazo)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 76153-18-9 3-(2-Chloro-phenyl)-5-(2-chloro-phenylazo)-6-hydroxy-1-(2-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 76153-25-8 5-(4-Bromo-phenylazo)-3-(2-chloro-phenyl)-6-hydroxy-1-(2-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 76153-32-7 3-(2-Chloro-phenyl)-6-hydroxy-1-(2-methoxy-phenyl)-2-thioxo-5-o-tolylazo-2,3-dihydro-1H-pyrimidin-4-one 
• 76153-39-4 3-(2-Chloro-phenyl)-6-hydroxy-1-(2-methoxy-phenyl)-2-thioxo-5-p-tolylazo-2,3-dihydro-1H-pyrimidin-4-one 
• 76153-11-2 3-(2-Chloro-phenyl)-6-hydroxy-1-(2-methoxy-phenyl)-5-phenylazo-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 

Relevant articles and documents

An "on-water" exploration of CuO nanoparticle catalysed synthesis of 2-aminobenzothiazoles

An "on-water" one-pot process has been engineered for the preparation of 2-aminobenzothiazole from ortho-halo (-F, -Cl, -Br and -I) substituted unsymmetrical thioureas. For ortho -I and -Br substrates the reactions afford 2-aminobenzothiazoles under metal free condition promoted by base. However, the relatively inert ortho -Cl and -F substrates undergo intramolecular arylthiolation only in the presence of CuO nanoparticles yielding 2-aminobenzothiazoles. This methodology provides easy access to aminobenzothiazoles utilising even the ortho -Cl and -F substrates. The catalyst is recyclable several times without loss of substantial activity. Other remarkable features include the wide range of functional group tolerance, absence of chromatographic purification (for ortho -I and -Br substrates) and providing moderate to excellent yield of the products under mild conditions, thus rendering the methodology as a highly eco-friendly alternative to the existing methods.