74327-95-0

Basic information

• Product Name: N-chloronortropane
• Synonyms: N-chloronortropane
• CAS NO: 74327-95-0
• Molecular Weight: 145.632
• Mol File: 74327-95-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-chloronortropane(CAS DataBase Reference)
• NIST Chemistry Reference: N-chloronortropane(74327-95-0)
• EPA Substance Registry System: N-chloronortropane(74327-95-0)

Safety Data

• Hazardous Substances Data: 74327-95-0(Hazardous Substances Data)

Upstream product

• 280-05-7 8-azabicyclo[3.2.1]octane 

Downstream Products

• 56847-10-0 8,8'-bi(8-azatricyclo<3.2.1>octane) 
• 643-20-9 pyrrolizidine 

Relevant articles and documents

Synthetic Approaches to Nortropanes and Nortrop-6-enes; Intramolecular Displacement by Nitrogen in 7-Membered Rings

The synthesis of simple nortropane and nortrop-6-ene derivatives from cyclohepta-1,3-diene is described.The key intermediates are trans-1-amino-4-chloro-cycloheptanes and -cyclohept-2-enes which are derived efficiently from the corresponding cis-amino-alcohols and undergo intramolecular cyclisation.Corresponding derivatisation of cyclohexa- and cycloocta-1,3-dienes is explored and attempts to achieve Pd-catalysed cyclisation of 1-amino-4-acetoxy-derivatives is described.Nitrogen inversion data for selected nortropane derivatives are included. Key Words: nortropanes/enes; 1,4-disubstitute cyclohexanes, cycloheptanes, cyclooctanes and -enes; intramolecular cyclisation; slow nitrogen inversion.