743476-52-0Relevant articles and documents
Synthesis of 1-benzyl-8,9-dihydroimidazo[4,5-c]pyrrolo[3,2-g]quinolin-4(5H) -one via palladium-catalyzed intramolecular arylation
Delest, Bruno,Tisserand, Jean-Yves,Robert, Jean-Michel,Nourrisson, Marie-Renée,Pinson, Patricia,Duflos, Muriel,Le Baut, Guillaume,Renard, Pierre,Pfeiffer, Bruno
, p. 6079 - 6083 (2004)
The synthesis of a novel tetracyclic structure, 8,9-dihydroimidazo[4,5-c] pyrrolo[3,2-g]quinolin-4(5H)-one, has been achieved by a convergent pathway. Coupling of the weakly nucleophilic hindered aromatic amine with 1-benzylimidazole-4-carboxylic acid, 7, afforded the corresponding amide 9 using a DCP/DMF complex; subsequent Heck-type arylation leading to desired tetracyclic molecule imidazo[4,5-c]-pyrrolo[3,2-g]quinolin-4(5H)-one.