743476-52-0

Upstream product

• 743476-49-5 6-nitro-N-pivaloylindoline 
• 743476-50-8 6-amino-N-pivaloylindoline 
• 42190-83-0 1-benzyl-4,5-imidazoledicarboxylic acid 
• 100-44-7 benzyl chloride 
• 123124-90-3 4,5-dicyano-1-(phenylmethyl)-1H-imidazole 
• 19727-83-4 6-nitroindoline 
• 496-15-1 1-indoline 
• 676372-30-8 1-benzyl-1H-imidazole-4-carboxylic acid 
• 743476-51-9 6-amino-5-bromo-N-pivaloylindoline 

Downstream Products

• 743476-53-1 N-(5-bromo-1-pivaloylindolin-6-yl)-N-methyl-(1-benzylimidazol-4-yl)carboxamide 

Relevant academic research and scientific papers

Synthesis of 1-benzyl-8,9-dihydroimidazo[4,5-c]pyrrolo[3,2-g]quinolin-4(5H) -one via palladium-catalyzed intramolecular arylation

The synthesis of a novel tetracyclic structure, 8,9-dihydroimidazo[4,5-c] pyrrolo[3,2-g]quinolin-4(5H)-one, has been achieved by a convergent pathway. Coupling of the weakly nucleophilic hindered aromatic amine with 1-benzylimidazole-4-carboxylic acid, 7, afforded the corresponding amide 9 using a DCP/DMF complex; subsequent Heck-type arylation leading to desired tetracyclic molecule imidazo[4,5-c]-pyrrolo[3,2-g]quinolin-4(5H)-one.