74366-48-6Relevant academic research and scientific papers
Amphiphilic organocatalyst for schotten-baumann-type tosylation of alcohols under organic solvent free condition
Asano, Keisuke,Matsubara, Seijiro
, p. 1757 - 1759 (2009)
A Tosylation of primary alcohol with tosyl chloride was performed effectively with an W-hexadecylimidazole catalyst in water containing K 2CO3 aggregation of the catalyst carrying a hydrophobic methylene chain worked as a substitute for organic solvent.
METHODS OF MAKING SUBSTITUTED PORPHYRIN PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS
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Page/Page column 38; 39, (2018/07/29)
Described herein are methods and intermediates useful for making substituted porphyrins, including Mn(III) orthoN-butoxyethylpyridylporphyrin, and compositions comprising the same. In some embodiments, a method of the present invention provides a composition having a certain percentage or yield (e.g., at least 80%, 85%, 90%, or 95% by weight) of a compound of the present invention.
Method for synthesizing cis-tritosylate
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Paragraph 0013, (2017/08/29)
The invention discloses a method for preparing cis-tritosylate. The cis-tritosylate shown in structural formula (II) is obtained by carrying out a reaction between a compound shown in structural formula (I) and toluene sulfonyl chloride in an anhydrous pyridine solvent according to an equal molar ratio. According to the method, use of an inorganic alkali catalyst Na2CO3 or K2CO3 is avoided, problems about hydrolysis of the toluene sulfonyl chloride are solved, and an obtained product is high in yield and free of other side reaction, and is not required to be separated by virtue of a method of column chromatography and the like.
Structural and Mechanistic Effects on the Rates of Ring-Opening Reactions in the 5-16-Membered-Ring Region
Cerichelli, Giorgio,Illuminati, Gabriello,Lillocci, Claudio
, p. 3952 - 3957 (2007/10/02)
Partial rate coefficients have been determined for the reaction of cyclic dimethylammonium ions with sodium methoxide in the 7-16-membered-ring region.Three second-order parallel reactions take place and lead to exocyclic demethylation (A), ring-opening substitution (B), and ring-opening olefin-forming elimination (C).The results were compared with the behavior of the five- and six-membered rings.Reaction A shows negligible dependence on ring size.In contrast, reactions B and C are affected by ring size through ring strain and geometry of the transition state: the latter factor is held responsible for major differences in the reactivity profiles between such reactions.
