74380-71-5

Basic information

• Product Name: 3-PROPIONYLBENZOIC ACID
• Synonyms: 3-PROPIONYLBENZOIC ACID;3-(1-oxopropyl)benzoic acid
• CAS NO: 74380-71-5
• Molecular Formula: C₁₀H₁₀O₃
• Molecular Weight: 178.18
• Mol File: 74380-71-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 351.1°C at 760 mmHg
• Flash Point: 180.3°C
• Appearance: /
• Density: 1.187g/cm³
• Vapor Pressure: 1.56E-05mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: 3-PROPIONYLBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PROPIONYLBENZOIC ACID(74380-71-5)
• EPA Substance Registry System: 3-PROPIONYLBENZOIC ACID(74380-71-5)

Safety Data

• Hazardous Substances Data: 74380-71-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H10O3/c1-2-9(11)7-4-3-5-8(6-7)10(12)13/h3-6H,2H2,1H3,(H,12,13)

Upstream product

• 19829-31-3 1-(3-bromophenyl)-1-propanone 
• 50916-34-2 3-propionylbenzonitrile 
• 554-12-1 propanoic acid methyl ester 
• 636-53-3 diethyl isophthalate 
• 1528-44-5 diisopropyl isophthalate 
• 1459-93-4 dimethyl Isophthalate 

Downstream Products

• 72563-47-4 3-propionylbenzoyl chloride 
• 115006-21-8 3-propionyl-benzoic acid methyl ester 
• 876762-31-1 C₁₇H₂₃NO₂ 
• 154320-61-3 3-benzoyl-α-chloro-propiophenone 
• 66952-39-4 1-(3-benzoylphenyl)propan-1-one 
• 454464-87-0 3-[3-(3-chloro-phenylamino)-2-mercapto-5-methyl-3H-imidazol-4-yl]-benzoic acid 
• 454464-57-4 3-[3-(3-chloro-phenylamino)-2-mercapto-5-methyl-3H-imidazol-4-yl]-benzamide 
• 554449-47-7 3-(2-mercapto-5-methyl-3-m-tolylamino-3H-imidazol-4-yl)-benzamide 
• 454464-58-5 3-[3-(3-chloro-phenylamino)-2-mercapto-5-methyl-3H-imidazol-4-yl]-benzoic acid methyl ester 
• 454464-86-9 3-(2-mercapto-5-methyl-3-m-tolylamino-3H-imidazol-4-yl)-benzoic acid methyl ester 
• 454464-55-2 rac-3-(2-bromo-propionyl)-benzoic acid methyl ester 

Relevant articles and documents

PIPERIDINE-AMIDE DERIVATIVES

The invention is concerned with novel piperidine-amide derivatives of formula (I) wherein R1, R2, X and Y are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These comp

Photochemical Rearrangement of α-Chloro-Propiophenones to α-Arylpropanoic Acids: Studies on Chirality Transfer and Synthesis of (S)-(+)-Ibuprofen and (S)-(+)-Ketoprofen

A new single-step efficient photochemical approach for α-arylpropanoic acids (4) from α-chloro-propiophenones (5) is described.It involves carbonyl triplet excited state directed 1,2-aryl migration of the aryl group which has been found to be highly dependent upon the nature of the aryl substituent.The mode of the rearrangement is probed by the study of the photobehaviour of a set of optically active α-chloro-propiophenones.The results suggest that the nature of the carbonyl triplets (n, ?*/ ?, ?*) plays an important role in the chirality transfer.This method finds application in the synthesis of optically active ibuprofen (4e) and ketoprofen (26), though in moderate optical yields.