74391-90-5Relevant academic research and scientific papers
Confocal and fluorescence lifetime imaging sheds light on the fate of a pyrene-tagged carbon monoxide-releasing Fischer carbene chromium complex
Arrowsmith, Rory L.,Atkin, Anthony J.,Botchway, Stanley W.,Fairlamb, Ian J. S.,Lynam, Jason M.,Moir, James W. B.,Pascu, Sofia I.,Ward, Jonathan S.,Zhang, Wei-Qiang
, p. 4957 - 4962 (2015)
The synthesis of a new pyrene-containing Fischer carbene complex is described. The complex has a broad absorbance spectrum between 300 and 400 nm and, on excitation at 345 nm in CH2Cl2 solution, emission is observed at 395 and 415 nm. Emission is also observed in PBS buffer, but in this case the resulting spectra are much broader. Confocal and fluorescence lifetime imaging indicate that emission occurs on treating HeLa cells with the complex and co-localisation studies demonstrate that this is from the mitochondria and lipid-rich regions of the cell. This journal is
P-Stereogenic monophosphines with the 2-p-terphenylyl and 1-pyrenyl substituents. Application to Pd and Ru asymmetric catalysis
Clavero, Pau,Grabulosa, Arnald,Font-Bardia, Mercè,Muller, Guillermo
, p. 183 - 190 (2014/06/10)
The synthesis of five optically pure P-stereogenic monophosphines of the type PPhArR (Ar = 2-p-terphenylyl (a), 1-pyrenyl (b); R = OMe, Me, i-Pr) is described. The ligands were fully characterised and the absolute configurations of PPh(1-pyrenyl)R (3b and 5b; R = OMe and Me respectively) were confirmed by X-ray diffraction. The complexation of the monophosphines to Pd and Ru organometallic units yielded the neutral complexes [PdCl(η3-2-Me- allyl)P] (10-12) and [RuCl2(η6-p-cymene)P] (16-18). Complete characterisation, including the crystal structure determination of [RuCl2(η6-p-cymene)(PMePh(2-p-terphenyl))] (17a) is provided. Neutral palladium complexes appeared as mixtures of two diastereomers in solution according to NMR. The synthesis and characterisation of four cationic [Pd(η3-2-Me-allyl)(P)2]PF6 (13 and 14) is also described. The application of neutral Pd complexes to catalytic styrene hydrovinylation afforded moderate conversions, high chemoselectivities (>92%) to 3-phenyl-1-butene and up to 43% ee with precursor 12a. Cationic Pd complexes were tested as catalytic precursors in allylic substitution of rac-3-acetoxy-1,3-diphenyl-1-propene (rac-I), with the anion of dimethylmalonate and benzylamine as nucleophiles, obtaining full conversions and up to 80% ee in alkylation and 60% ee in amination with precursor 13a. Finally, ruthenium complexes were used as catalytic precursors in transfer hydrogenation of acetophenone, with complete conversions after several hours but low enantioselectivities.
SURFACE MODIFICATION OF NANOSENSOR PLATFORMS TO INCREASE SENSITIVITY AND REPRODUCIBILITY
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Page/Page column 7, (2010/10/19)
The present invention relates to various methods of sensitizing and modifying nanosensor platforms. In one embodiment, the present invention provides a method of increasing sensitivity by inhibiting oxidation of one or more 1,4-hydroquinone (HQ) molecules
Novel catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids
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Page/Page column 4-5, (2008/06/13)
The present invention relates to a new method of cross-coupling aryl moieties comprising reacting an arylhalide with an arylboronic acid in the presence of a palladium compound and a compound comprising a di-alkylphosphine moiety.
SYNTHESIS OF POLYCYCLIC AROMATIC FLUORANTHENES
Cho, Bongsup P.,Harvey, Ronald G.
, p. 861 - 864 (2007/10/02)
A general synthetic approach to polycyclic aromatic hydrocarbons containing a fluoranthene ring system is described.The method entails fusion of an indeno ring to an alternant hydrocarbon via reaction of an aryllithium derivative with cyclohexene oxide.
