74412-93-4Relevant academic research and scientific papers
The solid phase synthesis of tertiary hydroxyesters from symmetrical diacid chlorides using organomanganese reagents
Leznoff, Clifford C.,Yedidia, Varda
, p. 287 - 290 (2007/10/02)
A 1percent crosslinked divinylbenzene-styrene copolymer, incorporating benzyl alcohol groups, was used to monoblock the symmetrical diacid chlorides.ClOC(CH2)nCOCl(where n=4 and 8).Further reaction of the polymer-bound monoester monoacid chloride with phenylmanganese iodide or butylmanganese iodide gave their respective polymer-bound tertiary hydroxyesters.Subsequent base cleavage and esterification yielded methyl 6-hydroxy-6,6-diphenylhexanoate, methyl 10-hydroxy-10,10-diphenyldecanoate, methyl 6-butyl-6-hydroxydecanoate, and methyl 10-butyl-10-hydroxytetradecanoate and some recovered dimethyl alkanoates.The reactions of some polymer-bound monoester monoacid chlorides with phenylcadmium chloride were also studied.
