74414-82-7

Upstream product

• 17466-00-1 7-chloro-3-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine 
• 151-50-8 potassium cyanide 
• 116944-02-6 6-benzoyl-6,7-dihydro-3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine-7-carbonitrile 
• 97-00-7 1-chloro-2,4-dinitro-benzene 

Downstream Products

• 134440-58-7 7-Morpholino-3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine 
• 134440-64-5 7-(Diethylamino)-8-ethyl-3-phenyl-3H-1,2,3-triazolo<4,5-d><1,3>diazocine-9-carbonitrile 
• 74502-77-5 7-anilino-3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine 
• 74414-81-6 2-phenyl-1-(3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine-7-carbonyl)hydrazine 
• 74414-77-0 N-hexyl-3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine-7-carboxamide 
• 74414-78-1 3,N-diphenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine-7-carboxamide 
• 74414-75-8 ethyl 3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine-7-carboxylate 
• 74414-80-5 3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine-7-carbohydrazide 
• 74414-79-2 3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine-7-carbohydroxamic acid 
• 74414-74-7 methyl 3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine-7-carboxylate 
• 74414-76-9 3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine-7-carboxylic acid 
• 74136-38-2 7-methyl-3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine 
• 74414-64-5 diethyl 3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine-7-malonate 
• 74528-93-1 7-benzylamino-3-phenyl-3H-1,2,3-triazolo<4,5-d>pyrimidine 

Relevant academic research and scientific papers

Preparation of Heteroarenecarbonitriles by Reaction of Haloheteroarenes with Potassium Cyanide Catalyzed by Sodium p-Toluenesulfinate

Several heteroarenecarbonitriles were prepared by reaction of haloheteroarenes with potassium cyanide catalyzed by sodium p-toluenesulfinate (1) or sodium methanesulfinate (2).In the reaction pathway, the cyanation proceeds through the formation of the su

Triazolo[4,5-d]pyrimidines. XII. Reactions of 6-benzoyl-6,7-dihydro-3-phenyl-3H-1,2,3-triazolo-[4,5-d]pyrimidines (triazolopyrimidine Reissert compounds) with acid, base, and electrophile

In the treatment of 6-benzoyl-6,7-dihydro-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine-7-car bonitrile (1, triazolopyrimidine Reissert compound) and 6-benzoyl-6,7-dihydro-5-methyl-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimid ine-7-carbonitrile (2,5-methyltriazolopyrimidine Reissert compound) with an acid, the ring fission of the pyrimidine ring proceeded to give the triazole derivatives (3-7). Alkaline hydrolysis of 2 and 1 gave 5-methyl-3-phenyl- (10) and 3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidines (9), respectively. The anions, generated from 1 and 2 with sodium hydride (NaH), underwent aromatization to give the 3H-1,2,3-triazolo[4,5-d]pyrimidine-7-carbonitriles (12 and 14). Compounds 1 and 2 reacted with arylaldehydes in the presence of NaH to give corresponding 3H-1,2,3-triazolo[4,5-d]pyrimidin-7-ylmethyl benzoates (15 and 17).

Triazolopyrimidines. V. The Nucleophilic Substitution of 7-Chloro- and 7-(p-Tolylsulfonyl)-3-phenyl-3H-1,2,3-triazolopyrimidines

The substitution reaction of 7-chloro- (1) and 7-(p-tolylsulfonyl)-3-phenyl-3H-1,2,3-triazolopyrimidines (2) with various nucleophiles (NuH or Nu(-)) was carried out.The reaction of 1 with amines (NuH-1 to NuH-11) gave 7-(N-substituted amino)-3-phe