74417-30-4

Usage

Uses

Used in Pharmaceutical Industry:
2,3-bis(benzylsulfanyl)naphthalene-1,4-dione is used as a potential therapeutic agent for its anti-tumor properties. It has shown to inhibit the growth of cancer cells, making it a promising candidate for further research and potential drug development.
Used in Anti-inflammatory Applications:
2,3-bis(benzylsulfanyl)naphthalene-1,4-dione is used as an anti-inflammatory agent due to its ability to reduce inflammation. Its potential use in treating inflammatory conditions is supported by its demonstrated effectiveness in in vitro and in vivo studies.
Used in Drug Development Research:
2,3-bis(benzylsulfanyl)naphthalene-1,4-dione is used as a subject of research in drug development. Its unique structure and biological activity make it a valuable candidate for exploring new therapeutic approaches to cancer and inflammatory diseases.

Upstream product

• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 
• 64-17-5 ethanol 
• 100-53-8 phenylmethanethiol 

Downstream Products

• 101445-82-3 2-benzylsulfanyl-3-hydroxy-[1,4]naphthoquinone 

Relevant academic research and scientific papers

Synthesis, electrochemistry, in-situ spectroelectrochemistry and molecular structures of 1,4-naphthoquinone derivatives

A novel series of 1,4-naphthoquinones substituted containing sulfur, nitrogen, oxygen atoms were synthesized. The structures of the novel products were characterized by using the various spectroscopic techniques such as 1H nuclear magnetic resonance (NMR), 13C NMR, mass spectrometry (MS), Fourier transform infrared spectroscopy (FT-IR) and microanalysis. The crystal structures of 2,3-bis(benzylsulfanyl)-1,4-napthoquinone 4 and 2,3-bis(ethylsulfanyl)-1,4-naphthoquinone 7 were determined by using X-ray single crystal diffraction method. Electrochemical behaviors of some 1,4-naphthoquinone (NQ) derivatives 3, 4, 7, 8, 9, 10, 12, 13, 15, 16, 17, 19 and 20 were studied by using cyclic voltammetry, square wave voltammetry and in-situ UV-Vis spectroelectrochemistry. The substituents of the NQ derivatives significantly altered the redox mechanism. In-situ UV-Vis spectroelectrochemical analyses of NQs supported the proposed redox mechanism.

Design, synthesis, biological evaluation, and antioxidant and cytotoxic activity of heteroatom-substituted 1,4-naphtho- and benzoquinones

In the present paper, we report the synthesis, characterization, and biological evaluation as antifungal, antibacterial, antioxidant, and cytotoxic/anticancer agents of N-, S-, O-substituted-1,4-naphtho- and 2,5-bis(amino-substituted)-1,4-benzoquinone der

Heterocyclic Quinonoid Chromophoric Systems : Part V - Synthesis of 3,4-Phthaloyl-2-thiaquinolizine

Condensation of α-mercaptomethylpyridine with 1,4-naphthoquinone, 2-chloro-1,4-naphthoquinone and 2,3-dichloro-1,4-naphthoquinone leads to a number of quinonoid derivatives including the desired 2-α-pyridylmethylmercapto-1,4-naphthoquinone (XVI) and its 3-chloro derivative (XI).Cyclization of XVI and XI gives 3,4-phthaloyl-2-thiaquinolizine (I) which represents a new heterocyclic quinonoid chromophoric system.Plausible mechanisms for the formation of the different heterocyclic quinones are discussed.Interaction of 1,4-naphthoquinone with 1-mercaptomethylisoquinoline affords 8,9-benzo-3,4-phthaloyl-2-thiaquinolizine (XXI).The thiaquinolizines undergo sulphur extrusion on heating to m.p. or on treatment with alkaline dithionite to yield the corresponding 2,3-phthaloylpyrrocolines.