744197-44-2 Usage
Uses
Used in Pharmaceutical Industry:
2-(AMINO-P-TOLYL-METHYL)-NAPHTHALEN-1-OL is used as a building block for the synthesis of pharmaceutical compounds due to its unique chemical structure and reactivity. Its potential applications in drug development include serving as an intermediate in the production of various medicinal agents.
Used in Dyes and Pigments Industry:
In the dyes and pigments industry, 2-(AMINO-P-TOLYL-METHYL)-NAPHTHALEN-1-OL is utilized as a precursor for the development of novel dyes and pigments. Its chemical properties allow for the creation of colorants with specific characteristics, such as improved stability and color intensity.
Used in Chemical Research:
2-(AMINO-P-TOLYL-METHYL)-NAPHTHALEN-1-OL is employed as a research molecule in chemical studies, particularly in the field of asymmetric organometallic catalysis. Its chiral nature makes it a promising candidate for use as a chiral ligand, which can enhance the selectivity and efficiency of catalytic reactions.
Used in Synthesis of Other Organic Compounds:
2-(AMINO-P-TOLYL-METHYL)-NAPHTHALEN-1-OL is used as a versatile building block in the synthesis of a wide range of organic compounds. Its unique structure and reactivity contribute to the development of new molecules with potential applications in various fields, such as materials science, agrochemicals, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 744197-44-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,4,1,9 and 7 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 744197-44:
(8*7)+(7*4)+(6*4)+(5*1)+(4*9)+(3*7)+(2*4)+(1*4)=182
182 % 10 = 2
So 744197-44-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H17NO/c1-12-6-8-14(9-7-12)17(19)16-11-10-13-4-2-3-5-15(13)18(16)20/h2-11,17,20H,19H2,1H3
744197-44-2Relevant academic research and scientific papers
High-performance liquid chromatographic enantioseparation of Betti base analogs on a newly developed isopropyl carbamate-cyclofructan6-based chiral stationary phase
Aranyi, Anita,Ilisz, Istvan,Pataj, Zoltan,Szatmari, Istvan,Fueloep, Ferenc,Armstrong, Daniel W.,Peter, Antal
experimental part, p. 549 - 556 (2012/01/05)
The direct separation of the enantiomers of 1-(α-aminoarylmethyl)-2- naphthol, 1-(α-aminoalkyl)-2-naphthol, 2-(α-aminoarylmethyl)-1- naphthol analogs, and 2-(1-amino-2-methylpropyl)-1-naphthol) was performed on a newly developed chiral stationary phase containing isopropyl carbamate-cyclofructan6 as chiral selector, with n-heptane/alcohol/ trifluoroacetic acid as mobile phase. The effects of the mobile-phase composition, the nature and concentration of the alcoholic and acidic modifiers, and the structures of the analytes on the retention and resolution were investigated. In some cases, separations were carried out at constant mobile-phase compositions in the temperature range 5-40°C. Thermodynamic parameters and Tiso values were calculated from plots of ln k′ or ln α versus 1/T. -Δ(ΔH°) ranged from 2.8 to 3.2 kJ mol-1, -Δ(ΔS°) from 7.7 to 10.1 J mol-1 K-1, and -Δ(ΔG°) from 0.2 to 0.5 kJ mol-1. It was found that the enantioseparations were enthalpy driven. The sequence of elution of the stereoisomers determined in some cases was (R) (S).
