74420-50-1 Usage
Uses
Used in Pharmaceutical Synthesis:
3-METHYL-5-AMINOIMIDAZO[1,2-A]PYRIDINE is used as a key intermediate in the synthesis of pharmaceutical compounds for its ability to contribute to the development of drugs with anti-cancer and anti-inflammatory effects. Its structural properties allow for the creation of molecules that can target specific biological pathways, making it a valuable component in medicinal chemistry.
Used in Research and Development:
In the scientific community, 3-METHYL-5-AMINOIMIDAZO[1,2-A]PYRIDINE is utilized as a research tool to study the effects of mutagenesis and carcinogenesis. Its mutagenic and carcinogenic properties provide insights into the mechanisms of DNA damage and repair, as well as the development of cancer, which can be instrumental in creating preventative measures or treatments.
Used in Quality Control and Safety Assessments:
Due to its recognized hazards, 3-METHYL-5-AMINOIMIDAZO[1,2-A]PYRIDINE is also employed in the quality control processes of laboratories and industries to ensure safety standards are met. It is used to test the efficacy of safety protocols and protective measures in handling potentially harmful chemicals, thereby contributing to a safer working environment.
Check Digit Verification of cas no
The CAS Registry Mumber 74420-50-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,4,2 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 74420-50:
(7*7)+(6*4)+(5*4)+(4*2)+(3*0)+(2*5)+(1*0)=111
111 % 10 = 1
So 74420-50-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H9N3/c1-6-5-10-8-4-2-3-7(9)11(6)8/h2-5H,9H2,1H3
74420-50-1Relevant academic research and scientific papers
Reaction of 3-Substituted Imidazopyridines with Br+ and the Alleged 5-Bromo-Substituted Product
Hand, E. Smakula,Paudler, William W.
, p. 3738 - 3745 (2007/10/02)
The reaction of 3-methylimidazopyridine with NBS was reinvestigated and is shown to give products formed by apparent nucleophilic substitution at the 2-position.NBS in CHCl3 gave compounds 4 and 6, while NBS in CCl4 or Br2 in CHCl3 gave exclusively 4.Mechanisms and differences in product formation are discussed; evidence that the previously reported NBS product was in fact 3-bromo-5-methylimidazopyridine, rather than the alleged 5-bromo-3-methyl derivative 3, is presented.Compound 3 was prepared by diazotization of 5-amino-3-methylimidazopyridine in the presence of HBr and by condensation of 2-bromopropanal (or its acetal) with 2-amino-6-bromopyridine (12).This latter reaction of the weakly basic aminopyridine 12 is shown to follow the normal pattern in which the amino nitrogen condenses with the carbonyl carbon.Structures are established by infrared, mass, and 1H-NMR spectral analyses, mechanistic considerations, and diagnostic reactions.Experimental and computer-generated 1H-NMR spectra of compounds 3 and 13 are reproduced.
