744217-14-9

Upstream product

• 1066-54-2 trimethylsilylacetylene 
• 135911-57-8 1-[3-O-(tert-butyldimethylsilyl)-2,5-dideoxy-β-L-glycero-pent-4-enofuranosyl]thymine 
• 128070-96-2 1-(3-O-acetyl-2,5-dideoxy-β-L-glycero-pent-4-enofuranosyl)thymine 
• 499970-82-0 1-(3-O-acetyl-2,5-dideoxy-5-iodo-β-D-threo-pentofuranosyl)thymine 
• 94892-66-7 1-(2,5-dideoxy-5-iodo-β-D-threo-pentofuranosyl)thymine 
• 744217-13-8 C₃₀H₃₆N₂O₈Si 
• 897037-31-9 1-[5-O-benzoyl-3-O-(tert-butyldimethylsilyl)-4-chloro-2-deoxy-β-D-threo-pentofuranosyl]thymine 
• 897037-32-0 1-[5-O-benzoyl-3-O-(tert-butyldimethylsilyl)-4-chloro-2-deoxy-α-L-erythro-pentofuranosyl]thymine 

Downstream Products

• 744217-15-0 1-[5-O-benzoyl-2-deoxy-4-C-ethynyl-β-D-threo-pentofuranosyl]thymine 
• 1067194-52-8 Benzoic acid (2R,3R,5R)-2-ethynyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-trifluoromethanesulfonyloxy-tetrahydro-furan-2-ylmethyl ester 

Relevant academic research and scientific papers

Anti-viral nucleoside analogs and methods for treating viral infections, especially HIV infections

The present invention relates to novel compounds according to the general formulas I, II, III, IV or V: wherein B is nucleoside base according to the structure: and the remaining variables as defined in the specification, and pharmaceutical compositions c

Nucleophilic substitution at the 4′-position of nucleosides: New access to a promising anti-HIV agent 2′,3′-didehydro-3′-deoxy- 4′-ethynylthymidine

For the synthesis of 2′,3′-didehydro-3′-deoxy-4′- ethynylthymidine (8: 4′-Ed4T), a recently reported promising anti-HIV agent, a new approach was developed. Since treatment of 1-(2,5-dideoxy-β-L- glyceropent-4-enofuranosyl)thymine with Pb(OBz)4