74423-06-6

Upstream product

• 53319-91-8 (E)-4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-3-en-2-yl acetate 
• 108204-11-1 (2E,4E)-5-iodo-3-methylpenta-2,4-dien-1-ol 
• 144950-81-2 <(E,E)-4-(2',6',6'-trimethylcyclohex-1'-en-1'-yl)buta-1,3-dien-1-yl>boronic acid 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 303779-99-9 (E)-2-(2,6,6-trimethylcyclohexen-1-yl)-ethenyl (trifluoromethyl)sulfonate 
• 475673-41-7 (E)-2-(2,6,6-trimethylcyclohexen-1-yl)ethenyl nonafluorobutanesulfonate 
• 472-66-2 (2,6,6-trimethyl-1-cyclohexen-1-yl)acetaldehyde 

Relevant academic research and scientific papers

Palladium-catalyzed coupling reaction of an enol nonaflate with (vinyl)tributylstannanes and acetylenes: A highly stereoselective synthesis of 8,18-13C2-labeled retinal

Here we report that enol nonaflates exhibit higher reactivity than the corresponding enol triflates in palladium-catalyzed cross-coupling reactions with various (vinyl)tributylstannanes and acetylenes. We also highlight the reaction of a vinyl nonaflate,

Palladium catalyzed coupling reaction of an enol nonaflate with (vinyl)tributylstannanes and acetylenes

A novel method for a stereoselective synthesis of trienes and dienynes was developed by palladium catalyzed cross coupling reactions of an enol nonaflate with (vinyl)tributylstannanes and acetylenes in good to excellent yields. Here, the enol nonaflate ex

The Suzuki Reaction in Stereocontrolled Polyene Synthesis: Retinol (Vitamin A), its 9- and/or 13-Demethyl Analogs, and Related 9-Demethyl-dihydroretinoids

A new synthesis of retinol (vitamin A) and 9- and/or 13-demethylretinols, with essentially complete control of regio- and stereochemistry, is described which is based on the thallium-accelerated, palladium-catalyzed cross-coupling reactions of (E)-1-alkenylboronic acids and (E)-1-alkenyl iodides (Suzuki reaction).The procedure has also been extended to the stereocontrolled synthesis of a series of 9-demethyl-dihydroretinoids of potential biological interest.

Reductive displacement of allylic acetates by hydride transfer via catalytic activation by palladium(0) complexes

Allylic acetates are reduced to alkenes by reductive displacement by hydride reagents via catalytic activation with Pd(0) complexes. In the absence of hydrides, allylic acetates afford conjugated dienes in DMSO solvent.