74425-67-5Relevant academic research and scientific papers
Catalytic enantioselective synthesis of sterically demanding alcohols using di(2°-alkyl)zinc prepared by the refined Charette's method
Hatano, Manabu,Mizuno, Tomokazu,Ishihara, Kazuaki
supporting information; experimental part, p. 5443 - 5445 (2010/10/04)
A highly practical, catalytic enantioselective 2°-alkyl addition to aldehydes and ketones was developed. Chiral phosphoramide ligand (1) with salt-free and solvent-free di(2°-alkyl)zinc reagents prepared from (2°-alkyl)MgCl was essential. The Royal Society of Chemistry 2010.
Synthesis of Optically Active 2-Furylmethanols as Useful Chiral Building Blocks and Its Application to the Synthesis of (5R,6S)-6-Acetoxyhexadecan-5-olide and (+)-Disparlure
Kametani, Tetsuji,Tsubuki, Masayoshi,Tatsuzaki, Yoko,Honda, Toshio
, p. 639 - 646 (2007/10/02)
Kinetic resolution of racemic secondary 2-furylmethanols using catalytic amounts of the titanium(IV)-tartrate complex was achieved successfully, providing optically active 2-furylmethanols (80 - >98percent ee) and corresponding pyranones. (S)-1-(2-Furyl)undecanol (1f) was utilised as a chiral building block in the synthesis of (5R,6S)-6-acetoxyhexadecan-5-olide and (+)-disparlure.
