74440-02-1

Basic information

• Product Name: (Z)-2-(2-Aminothiazol-4-yl)-2-(tert-butoxycarbonylmethoxyimino)acetic acid
• Synonyms: (Z)-2-(2-Aminothiazol-4-yl)-2-(tert-butoxycarbonylmethoxyimino)acetic acid;AT-TMA;(2-AMINOTHIAZOL-4-YL)-TERT-BUTOXYCARBONYLMETHOXYIMINO ACETIC ACID;(Z)-2-(2-Aminothiazoi-4-yl)-2-(2-tert-butoxycarbonylprop-2-oxyimino)aceticacid;AT-TMA： (Z)-2-(2-Aminothiazoi-4-yl)-2-(2-t-butoxycarbonylprop-2-oxyimino) acetic acid;(Z)-2-(2-aminothiazol-4-yl)-2-t-butoxycarbonyl methoxyimino) acetic Acid (AT-TMA or TBCA);ASTRAGALUSROOTRGBRM;(aZ)-2-Amino-α-[[2-(1,1-dimethylethoxy)-2-oxoethoxy]imino]-4-thiazoleacetic Acid
• CAS NO: 74440-02-1
• Molecular Formula: C₁₁H₁₅N₃O₅S
• Molecular Weight: 301.32
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
• Mol File: 74440-02-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 175-176 °C (decomp)
• Boiling Point: 482.8 °C at 760 mmHg
• Flash Point: 245.8 °C
• Appearance: /
• Density: 1.43 g/cm³
• Vapor Pressure: 3.93E-10mmHg at 25°C
• Refractive Index: 1.601
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: DMSO, Methanol (Sparingly)
• PKA: 2?+-.0.10(Predicted)
• CAS DataBase Reference: (Z)-2-(2-Aminothiazol-4-yl)-2-(tert-butoxycarbonylmethoxyimino)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-(2-Aminothiazol-4-yl)-2-(tert-butoxycarbonylmethoxyimino)acetic acid(74440-02-1)
• EPA Substance Registry System: (Z)-2-(2-Aminothiazol-4-yl)-2-(tert-butoxycarbonylmethoxyimino)acetic acid(74440-02-1)

Safety Data

• Hazardous Substances Data: 74440-02-1(Hazardous Substances Data)

Usage

Uses

A cephalosporin derivatives

InChI:InChI=1/C11H15N3O5S/c1-11(2,3)19-7(15)4-18-14-8(9(16)17)6-5-20-10(12)13-6/h5H,4H2,1-3H3,(H2,12,13)(H,16,17)/b14-8-

Downstream Products

• 204185-34-2 [1-(2-Amino-thiazol-4-yl)-2-(diethoxy-phosphoryloxy)-2-oxo-eth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 

Relevant articles and documents

4-Carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production

Disclosed are compounds of the general formula: STR1 wherein R1 is a hydrogen atom or a lower alkyl group and R2 is a hydrogen atom or an ester residue, said derivative having the (3S,4S)-configuration; and pharmaceutically acceptable salts and esters thereof. The compounds have antimicrobial and/or β-lactamase-inhibitory activity and are of value as drugs for human beings and domesticated animals.