74441-23-9Relevant academic research and scientific papers
Stereoselective Reduction of Indoline Nitroxide Radicals
Berti, Corrado,Greci, Lucedio,Poloni, Marino
, p. 710 - 713 (2007/10/02)
1,2-Dihydro-2-alkyl-2-phenyl-3H-indol-3-one 1-oxyls (1) and the corresponding amines (6) undergo stereoselective reduction with NaBH4 giving respectively a pair of diastereoisomeric hydroxylamines (2), (3) and the corresponding amines (7), (8).Both lead to nitroxide radicals (4) and (5), by oxidation; the quantitative ratio of diastereoisomers was determined by liquid-liquid chromatography.The configurations of the isomers are tentatively assigned on the basis of (1)H n.m.r. and e.s.r. data, as well as on the stereochemistry of the reaction.
