74441-59-1

Upstream product

• 88-15-3 2-Acetylthiophene 
• 89-98-5 2-chloro-benzaldehyde 

Downstream Products

• 1160496-30-9 C₁₉H₁₃Cl₂NS₂ 
• 1160496-34-3 C₂₁H₁₈ClNOS₂ 
• 1160496-32-1 C₂₀H₁₆ClNS₂ 
• 1160496-29-6 C₁₉H₁₃ClFNS₂ 
• 1160496-31-0 C₁₉H₁₃BrClNS₂ 
• 1160496-33-2 C₂₀H₁₆ClNOS₂ 
• 79442-58-3 (o-chlorophenyl)-4 dihydro-4,5 6H-thieno<2,3-c>pyridinone-7 
• 79442-65-2 (o-chlorophenyl)-4 dihydro-4,5 7H-thieno<2,3-b>pyridinone-6 
• 149280-51-3 4-(2-Chloro-phenyl)-4,5-dihydro-cyclopenta[b]thiophen-6-one 

Relevant academic research and scientific papers

Syntheses of 1,5-benzothiazepines: Part XXXVI - Syntheses and antimicrobial evaluation of 2-(2-chlorophenyl)-4-(4-chlorophenyl/2-thienyl)-2,5-dihydro-8- substituted-1,5-benzothiazepines

Six 5-substituted-2-aminobenzenethiols have been reacted with 3-(2-chlorophenyl)-1-(4-chlorophenyl)-2-propenone and 3-(2-chlorophenyl)-1-(2- thienyl)-2-propenone in dry ethanol saturated with dry HCl gas, to obtain twelve new compounds, 8-substituted-2-(2-chlorophenyl)-4-(4-chlorophenyl/2-thienyl)-2, 5-dihydro-1,5-benzothiazepines in satisfactory yields. The structures of the final products have been assigned by elemental microanalyses data for elements, C, H, and N and by IR, 1H NMR, and mass spectroscopies. The synthesized compounds have been evaluated for their relative antimicrobial activity against the gram-positive bacteria, Staphylococcus aureus, gram-negative bacteria, Pseudomonas aeruginosa and the fungus, Candida albicans. The compounds have been found to show little antibacterial activity, but interestingly, showed significant antifungal activity. Copyright Taylor & Francis Group, LLC.