74457-25-3Relevant academic research and scientific papers
Synthesis of spiranes by thiol-mediated acyl radical cyclization
Hsu, Day-Shin,Chen, Chih-Hao,Hsu, Chi-Wei
, p. 589 - 598 (2016/02/18)
A general and efficient method for the preparation of spiro compounds is described. Various enone-aldehydes were exposed to t-dodecanethiol and AIBN at 75 °C in toluene to afford spirocyclic 1,4-diketones in moderate to good yields. Intramolecular acyl radical cyclization of a series of enone-aldehydes in the presence of AIBN and a thiol was studied. Various ring size of the all-carbon spirocyclic 1,4-diketones were obtained in moderate to good yields.
Intramolecular azide-alkene 1,3-dipolar cycloaddition/enamine addition(s) cascade reaction: Synthesis of nitrogen-containing heterocycles
De Miguel, Irene,Herradon, Bernardo,Mann, Enrique
, p. 1731 - 1736 (2012/07/28)
A cascade intramolecular azide-alkene 1,3-dipolar cycloaddition/1,2 enamine and/or 1,4 enamine addition reaction sequence has been developed, and provides access to a variety of nitrogen containing heterocycles from readily available ω-azido alkenes. Copy
Spiranes synthesis based on samarium diiodide-mediated reductive cyclization
Hsu, Day-Shin,Hsu, Chi-Wei
supporting information; experimental part, p. 2185 - 2188 (2012/05/20)
A general and efficient method for the preparation of spiro compounds is described. Enone-aldehydes were exposed to samarium diiodide under mild conditions and various spirocyclic γ-hydroxyketones were obtained in good yields.
Samarium diiodide-mediated intramolecular cyclodimerisation of bis-α,β-unsaturated carbonyl compounds
Powell, Jonathan R.,Dixon, Sally,Light, Mark E.,Kilburn, Jeremy D.
scheme or table, p. 3564 - 3567 (2009/10/26)
Samarium(II) diiodide-mediated intramolecular cyclodimerisation of simple bis-enones and -enoates in THF/MeOH has been investigated. Spirocyclic and elaborated polycyclic products, including stereodefined cis-bicyclo[3.3.0]octane and trans-bicyclo[4.3.0]n
Amberlyst-15-catalyzed intramolecular S(N)2' oxaspirocyclization of tertiary allylic alcohols
Young, Jenn-Jong,Jung, Liarng-Jyur,Cheng, Kuang-Ming
, p. 3411 - 3413 (2007/10/03)
A variety of substituted 1-oxaspiro[4.5]dec-6-ene and 1- oxaspiro[5.5]undec-7-ene systems have been prepared by utilizing Amberlyst- 15-catalyzed S(N)2' oxaspirocyclizations under mild reaction conditions (- 20°C) in quantitative yields. In this process,
Palladium-Catalyzed Preparation of Carbon and Oxygen Spirocycles
Godleski, Stephen A.,Valpey, Richard S.
, p. 381 - 383 (2007/10/02)
A variety of substituted spiroundecene and spirodecene systems have been prepared by utilizing ?-allylpalladium chemistry in the key ring-forming step.
