74458-10-9

Upstream product

• 60526-02-5 (E)-3-Dimethylamino-2-((3aS,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-acrylonitrile 

Downstream Products

• 86132-79-8 7-((3aS,4S,6R,6aR)-2,2-Dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-furo[3,2-d]pyrimidin-4-ylamine 
• 104011-37-2 7-((3aS,4R,6R,6aR)-2,2-Dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-furo[3,2-d]pyrimidin-4-ylamine 
• 86132-77-6 3-Amino-4-((3aS,4S,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-furan-2-carbonitrile 
• 86132-78-7 3-Amino-4-((3aS,4R,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-furan-2-carbonitrile 
• 103931-21-1 (E)-3-Cyanomethoxy-2-((3aS,6R,6aR)-2,2-dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-acrylonitrile 

Relevant academic research and scientific papers

SYNTHESIS OF FUROPYRIMIDINE NUCLEOSIDES: A NOVEL C-NUCLEOSIDE ISOSTERE OF ADENOSINE

The synthesis of 4-amino-7-(β-D-ribofuranosyl)-furopyrimidine, a new C-nucleoside analog of adenosine, is described.It involves base-catalyzed cyclization of the 2-(ribofuranosyl)-2-cyano ethers 3 to afford the ribosyl-3-amino-2-cyanofurans 4α and