74473-07-7Relevant academic research and scientific papers
Conjugate Addition of the Anion Derived from 3-(Phenylsulfinyl)prop-1-ene to Cyclopent-2-en-1-one
Binns, Malcolm R.,Haynes, Richard K.,Houston, Timothy L.,Jackson, W. Roy
, p. 2465 - 2467 (2007/10/02)
The title anion in tetrahydrofuran containing one equivalent of hexamethylphosphoric triamide at -78 deg undergoes a rapid conjugate addition reaction with cyclopent-2-en-1-one.The sole product obtained, in 73percent yield, is (E)-3-3-(phenylsulfinyl)pro
HMPA-MEDIATED CONJUGATE ADDITION OF ALKYL- AND PHENYLTHIOALLYL ANIONS TO CYCLOPENTENONE
Binns, Malcolm R.,Haynes, Richard K.,Houston, Timothy L.,Jackson, W. Roy
, p. 573 - 576 (2007/10/02)
One equivalent of HMPA induces 1,4-addition of the title anions predominantly through the α-position to cyclopentenone in THF at -78 deg C.In THF alone irreversible addition takes place to give mixtures comprising largely α- and γ-1,2 products.
