74474-48-9Relevant academic research and scientific papers
Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist
Epifano, Francesco,Genovese, Salvatore,James Squires,Gray, Matthew A.
scheme or table, p. 3130 - 3135 (2012/06/04)
A series of 29 oxyprenylated and azoprenylated phenylpropanoids were chemically synthesized and tested in transfected cultured HepG2 cells by means of the dual-luciferase assay as farnesoid X receptor (FXR) agonists, using the endogenous ligand chenodeoxy
Syntheses of two cytotoxic sinapyl alcohol derivatives and isolation of four new related compounds from Ligularia nelumbifolia
Zhao, Yu,Hao, Xiaojiang,Lu, Wei,Cai, Junchao,Yu, Hong,Sevenet, Thierry,Gueritte, Francoise
, p. 902 - 908 (2007/10/03)
Phytochemical reinvestigation on Ligularia nelumbifolia afforded four novel sinapyl alcohol analogues named nelumols B-E (1-4) and three known sinapyl alcohol derivatives (5-7). Their structures were elucidated by NMR techniques. Total syntheses of cytotoxic geranyloxy sinapyl alcohol (6) and geranyloxy sinapyl aldehyde (7) were carried out via two different paths. The 4-O-benzyl-substituted analogues (20 and 27) as well as the 4-O-(2-methylbutenyl) derivatives (34 and 35) were also synthesized. The cytotoxicities of 6 and 7 were measured using A-549, HL-60, and KB cancer cell lines.
EIN NEUES SYRINGAALKOHOL-DERIVAT AUS ERECHTITES HIERACIFOLIA
Bohlmann, Ferdinand,Abraham, Wolf-Rainer
, p. 469 - 470 (2007/10/02)
Key Word Index - Erechtites hieracifolia; Compositae; new syringyl alcohol derivative.
