74474-60-5

Upstream product

• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 634922-73-9 1-(3-methoxy-4-methoxymethoxyphenyl)-3-(2,4-dimethoxyphenyl)-1-propanol 
• 634922-72-8 2,4',4-trimethoxymethoxy-3'-methoxychalcone 
• 634922-70-6 1-(3-methoxy-4-methoxymethoxyphenyl)ethanol 
• 121-33-5 vanillin 
• 143418-77-3 1-<3-methoxy-4-(methoxymethoxy)phenyl>ethanone 
• 5533-00-6 3-methoxy-4-methoxymethoxy-benzaldehyde 
• 634922-74-0 (+/-)-7,4'-dimethoxymethoxy-3'-methoxyflavan 

Downstream Products

• 98437-88-8 7,3',4'-trimethoxyflavan 

Relevant academic research and scientific papers

Studies on flavans. III. The total synthesis of (±)-7,4′ -dihydroxy-3′-methoxyflavan, (±)-7,3′-dihydroxy-4′ -methoxyflavan, and (±)-7,4′-dihdroxyflavan

The first total synthesis of (±)-7,3′-dihydroxy-4′ -methoxyflavan (1) and (±)-7,4′-dihydroxy-3′-methoxyflavan (2), along with the synthesis of (±)-7,4′-dihydroxyflavan (3), three naturally occurring flavans, were described. The key step is the cyclization of 1,3-diaryl-1-propanol by BF3·Et2O.

FLAVONOID AND OTHER CONSTITUENTS OF BAUHINIA MANCA

Phytochemical analysis of the stem of Bauhinia manca yielded 63 compounds, among them six new natural products.Major constituents were found to be 3-O-galloylepicatechin, gallic acid, cinnamic acid, β-sitosterol and its β-D-glucoside.The two new flavans possess significant antifungal activity.Key Word Index-Bauhinia manca; Leguminosae; 5,5-dimethoxylariciresinol; 4-O-methylisoliquiritigenin; 4'-O-methylliquiritigenin; 7,3'-dimethoxy-4-hydroxyflavan; 3',4'-dihydroxy-7-methoxyflavan; 2,4'-dihydroxy-4-methoxydihydrochalcone; antimicrobial activity.