74476-05-4

Basic information

• Product Name: (E)-3-(4-hydroxyphenyl)-1-(pyrazin-2-yl)prop-2-en-1-one
• Synonyms: (E)-3-(4-hydroxyphenyl)-1-(pyrazin-2-yl)prop-2-en-1-one
• CAS NO: 74476-05-4
• Molecular Weight: 226.235
• Mol File: 74476-05-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-3-(4-hydroxyphenyl)-1-(pyrazin-2-yl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(4-hydroxyphenyl)-1-(pyrazin-2-yl)prop-2-en-1-one(74476-05-4)
• EPA Substance Registry System: (E)-3-(4-hydroxyphenyl)-1-(pyrazin-2-yl)prop-2-en-1-one(74476-05-4)

Safety Data

• Hazardous Substances Data: 74476-05-4(Hazardous Substances Data)

Upstream product

• 22047-25-2 acetylpyrazine 
• 123-08-0 4-hydroxy-benzaldehyde 

Relevant articles and documents

Ring substituted 3-phenyl-1-(2-pyrazinyl)-2-propen-1-ones as potential photosynthesis-inhibiting, antifungal and antimycobacterial agents

Four series of ring substituted (E)-3-phenyl-1-(2-pyrazinyl)-2-propen-1-ones were prepared by means of modified Claisen-Schmidt condensation of acetylpyrazines with aromatic aldehydes. The structures were confirmed by elemental analysis, IR, 1H NMR and 13C NMR spectra. The compounds were tested for specific biological properties and some derivatives exhibited photosynthesis-inhibiting, antifungal and antimycobacterial properties. The most pronounced effects were observed with compounds substituted with phenolic groups. Ortho-hydroxyl substituted derivatives were more potent than the corresponding para-hydroxyl substituted analogues.

Darstellung und Strukturbestimmung einiger Diazachalkone

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