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2-chloro-3-(4-fluorophenyl)-3-oxopropanoic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

74476-70-3

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74476-70-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 74476-70-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,4,7 and 6 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 74476-70:
(7*7)+(6*4)+(5*4)+(4*7)+(3*6)+(2*7)+(1*0)=153
153 % 10 = 3
So 74476-70-3 is a valid CAS Registry Number.

74476-70-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloro-3-(4-fluoro-phenyl)-3-oxo-propionic acid ethyl ester

1.2 Other means of identification

Product number -
Other names ethyl 2-chloro-3-(4-fluoro-phenyl)-3-oxo-propionate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:74476-70-3 SDS

74476-70-3Relevant articles and documents

Highly diastereoselective and enantioselective synthesis of α-hydroxy β-amino acid derivatives: Lewis base catalyzed hydrosilylation of α-acetoxy β-enamino esters

Jiang, Yan,Chen, Xing,Zheng, Yongsheng,Xue, Zhouyang,Shu, Chang,Yuan, Weicheng,Zhang, Xiaomei

supporting information; experimental part, p. 7304 - 7307 (2011/09/16)

By design: A series of α-acetoxy-β-enamino esters 1 were synthesized and then subjected to catalytic asymmetric hydrosilylation. In the presence of a chiral Lewis base catalyst, the reactions proceeded smoothly to provide a wide range of chiral α-acetoxy β-amino acid derivatives in high yields with good diastereoselectivities and enantioselectivities. Copyright

OXAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS

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Page/Page column 47, (2010/04/27)

The invention relates to oxazolidine derivatives of the formula (I) wherein A, B, and R1 are as described in the description, to salts, especially pharmaceutically acceptable salts, of such compounds and to their use as medicaments, especially

PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES

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Page/Page column 100, (2010/04/30)

The invention relates to novel phenethylamide derivatives and their heterocyclic analogues of formula (I), wherein A, B, R1, R2 and R3 are as described in the application, and to the use of such compounds, or of pharmaceut

PYRAZOLE COMPOUNDS AND USE THEREOF

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Page/Page column 36, (2009/05/29)

The pyrazole compound of the present invention is represented by the following general formula (I). The pyrazole compound of the present invention or a salt thereof or a solvate thereof potently inhibits liver glycogen phosphorylase, and, therefore, is useful as a therapeutic or prophylactic agent for diabetes. wherein each symbol denotes as described in the specifications.

TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES

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Page/Page column 68, (2009/03/07)

The invention relates to novel trans-3-aza-bicyclo[3.1.0]hexane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

Syntheses and Reactions of 2-Halo-5-thiazolecarboxylates

Lee, Len F.,Schleppnik, Francis M.,Howe, Robert K.

, p. 1621 - 1630 (2007/10/02)

A variety of 2-halo-5-thiazolecarboxylates was prepared from substituted-3-aminoacrylates and 3-ketoesters.Selective reduction of 2-chloro-5-thiazolecarboxylates 4a, 4i and 4j with sodium borohydride in ethanol provided the corresponding 2-halo-5-thiazolemethanols 27 - 29.Nucleophilic displacement on methyl methanesulfonate (32c) occured selectivity at the 5-substituent to provide 2-chloro-4-(trifluoromethyl)-5-(heteroatom-substituted methyl)thiazoles 32d-f.

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