74480-93-6Relevant academic research and scientific papers
Regioselective synthesis of ω-bromo-3-ketosulfones, ω-bromo-3-ketonitriles and 2-(ω-bromoalkyl)benzofurans based on a 'ring-closing/ring-opening' strategy
Rasool, Nasir,Rashid, Muhammad A.,Reinke, Helmut,Fischer, Christine,Langer, Peter
, p. 11626 - 11635 (2008/03/13)
ω-Bromo-3-ketosulfones, ω-bromo-3-ketonitriles and various functionalized 2-(ω-bromoalkyl)benzofurans were chemo- and regioselectively prepared by application of a 'ring-closing/ring-opening' strategy. The cyclization of 3-ketosulfone and 3-ketonitrile dianions with 1-bromo-2-chloroethane or 1,4-dibromobut-2-ene afforded functionalized 2-alkylidenetetrahydrofurans which were subsequently cleaved by reaction with boron tribromide or boron trichloride to give the final products.
5 - And 6 - membered ring compounds from (E)-β-iodo(vinyl)sulfones
Short, Kevin M.,Ziegler Jr., Carl B.
, p. 355 - 356 (2007/10/02)
Appropriately functionalized alkynes are converted to (E)-β-iodo(vinyl)sulfones which, in turn, furnish cyclic products on treatment with base.
Reaction between 1,1-Dithioalkyl Phenyl Sulphones and ω-Bromoesters. Synthesis of Cyclic Vinyl Ethers
Mussatto, Maria Cristina,Savoia, Diego,Trombini, Claudio,Umani-Ronchi, Achille
, p. 260 - 263 (2007/10/02)
The reaction between 1,1-dithioalkyl phenyl sulphones (11) and ethyl 4-bromobutyrate affords tetrahydro-2-furylidene derivatives (13) together with minor amounts of the cyclopropyl ketones (15).A mixture of the cyclohexanone and dihydropyran derivatives (17) and (18), respectively, is obtained by the reaction of (11) with ethyl 5-bromovalerate.Treatment of the ω-bromo-β-ketosulphone (19) with various basic reagents also gives a mixture of (17) and (18).
