74483-52-6

Usage

Uses

Used in Pharmaceutical Industry:
BENZENE, 1-FLUORO-2-METHYL-4-(TRIFLUOROMETHYL)is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of novel drug molecules with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, BENZENE, 1-FLUORO-2-METHYL-4-(TRIFLUOROMETHYL)is utilized as a building block for the creation of agrochemicals, enhancing the effectiveness of products designed to protect crops and improve agricultural yields.
Used in Specialty Chemicals Production:
BENZENE, 1-FLUORO-2-METHYL-4-(TRIFLUOROMETHYL)is employed as a precursor in the production of specialty chemicals, which are high-value compounds used in various industries for their unique properties and applications.
Used as an Industrial Solvent:
BENZENE, 1-FLUORO-2-METHYL-4-(TRIFLUOROMETHYL)is used as a solvent in various industrial processes, capitalizing on its ability to dissolve a wide range of substances and facilitate chemical reactions.

InChI:InChI=1/C8H6F4/c1-5-4-6(8(10,11)12)2-3-7(5)9/h2-4H,1H3

Upstream product

• 352-70-5 m-Fluorotoluene 
• 929000-62-4 1-bromo-2-methyl-4-(trifluoromethyl)benzene 

Relevant academic research and scientific papers

Metal-Catalyzed Carbon-Fluorine Bond Formation

One aspect of the invention relates to a metal-catalyzed conversion of aryl halides and sulfonates to the corresponding aryl fluorides. Another aspect of the invention relates to a metal-catalyzed conversion of heteroaryl halides and sulfonates to the corresponding heteroaryl fluorides. Another aspect of the invention relates to a metal-catalyzed conversion of vinyl halides and sulfonates to the corresponding vinyl fluorides. In certain embodiments, simple fluoride sources, such as AgF and CsF, are used. In certain embodiments, the transformations tolerate a wide range of functional groups, allowing for introduction of fluorine atoms into highly functionalized organic molecules.

Formation of arf from lpdar(f): catalytic conversion of aryl triflates to aryl fluorides

Despite increasing pharmaceutical importance, fluorinated aromatic organic molecules remain difficult to synthesize. Present methods require either harsh reaction conditions or highly specialized reagents, making the preparation of complex fluoroarenes ch

Process for the preparation of aromatic trifluoromethyl compounds

A process for the preparation of an aromatic trifluoromethyl compound which comprises contacting an aromatic compound of the formula STR1 wherein R1 denotes hydrogen, alkyl, aryl, aralkyl, aryloxy, arylthio, polyhalogenoalkoxy or polyhalogenoalkylthio and the aromatic substituents R1 can in turn be substituted by halogen, alkyl, polyhalogenoalkyl, polyhalogenoalkoxy, polyhalogenoalkylthio, nitro, chlorocarbonyl or chlorosulfonyl, and R2, R3, R4 and R5 are independently hydrogen, halogen or alkyl and two adjacent radicals of the group R1 to R5 can conjointly form a three-membered to five-membered alkylene radical, with carbon tetrachloride and hydrogen fluoride at a temperature in the range of 50° C. to 140° C. Certain new aromatic trifluoromethyl compounds which can prepared by such a process are also disclosed.