74484-67-6

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-((4-(2-methyl-1-piperidinyl)-2-butynyl)o xy)-
• Synonyms: 1H-Isoindole-1,3(2H)-dione, 2-((4-(2-methyl-1-piperidinyl)-2-butynyl)o xy)-
• CAS NO: 74484-67-6
• Molecular Formula: C18H20 N2 O3
• Molecular Weight: 0
• Mol File: 74484-67-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 457.1°C at 760 mmHg
• Flash Point: 230.3°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 1.53E-08mmHg at 25°C
• Refractive Index: 1.617
• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-((4-(2-methyl-1-piperidinyl)-2-butynyl)o xy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-((4-(2-methyl-1-piperidinyl)-2-butynyl)o xy)-(74484-67-6)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-((4-(2-methyl-1-piperidinyl)-2-butynyl)o xy)-(74484-67-6)

Safety Data

• Hazardous Substances Data: 74484-67-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C18H20N2O3/c1-14-8-4-5-11-19(14)12-6-7-13-23-20-17(21)15-9-2-3-10-16(15)18(20)22/h2-3,9-10,14H,4-5,8,11-13H2,1H3

Upstream product

• 50-00-0 formaldehyd 
• 4616-63-1 2-(prop-2-yn-1-yloxy)isoindoline-1,3-dione 
• 109-05-7 2-Methylpiperidin 

Relevant articles and documents

Synthesis and biological evaluation of N-(4-t-amino-2-butynyloxy) and N-(4-t-amino-2-butynyl) phthalimides

A series of N-(4-t-amino-2-butynyloxy) and N-(4-t-amino-2-butynyl) phthalimides have been prepared through the Mannich reaction from N-(propargyloxy) phthalimide or N-propargylphthalimide with formaldehyde and various cyclic amines. These compounds have been investigated for blockade of oxotremorine in intact mice, and for their antagonistic activity towards acetylcholine on isolated guinea pig ileal preparations. None of the oxyphthalimido derivatives show oxotremorine antagonistic activity, but all have an acetylcholine antagonistic activity. The phthalimido compounds, on the other hand, have both oxotremorine and acetylcholine antagonistic activity.