74491-45-5Relevant academic research and scientific papers
Ni(ii)-salt catalyzed activation of primary amine-sp3C α-H and cyclization with 1,2-diketone to tetrasubstituted imidazoles
Samanta, Srikanta,Roy, Dipanwita,Khamarui, Saikat,Maiti, Dilip K.
supporting information, p. 2477 - 2480 (2014/03/21)
NiCl2·6H2O and Ni(OAc)2· 4H2O were found as efficient catalysts for C-H activation of benzyl and aliphatic amines for an unprecedented multi C-N bond forming cyclization with 1,2-diketones under refluxing toluene to furnish highly substituted and polycyclic imidazoles.
The Reaction between Cyanide Ion and Nitrones; a Novel Imidazole Synthesis
Cawkill, Eric,Clark, Nigel G.
, p. 244 - 248 (2007/10/02)
By contrast with the CN-diphenylnitrones, cold aqueous ethanolic potassium cyanide converts N-methyl-C-phenylnitrone into 1-methyl-4,5-diphenylimidazole.The scope of this reaction has been investigated, and shown to proceed via intermediate cyano-imines, some of which have been synthesised by alternative routes.
