74495-73-1

Basic information

• Product Name: 3-Hydroxy-4-methoxybenzaldehyde-d3
• Synonyms: 3-Hydroxy-4-methoxybenzaldehyde-d3;2-Methoxy-5-forMylphenol-d3;3-Hydroxy-4-(trideuteroMethoxy)benzaldehyde;3-Hydroxyanisaldehyde-d3;5-ForMyl-2-Methoxyphenol-d3;5-ForMylguaiacol-d3;Isovanillin-d3;NSC 82996-d3
• CAS NO: 74495-73-1
• Molecular Formula: C8H5D3O3
• Molecular Weight: 155.165805334
• Product Categories: Aromatics;Isotope Labelled Compounds
• Mol File: 74495-73-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Methanol
• CAS DataBase Reference: 3-Hydroxy-4-methoxybenzaldehyde-d3(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hydroxy-4-methoxybenzaldehyde-d3(74495-73-1)
• EPA Substance Registry System: 3-Hydroxy-4-methoxybenzaldehyde-d3(74495-73-1)

Safety Data

• Hazardous Substances Data: 74495-73-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-Hydroxy-4-methoxybenzaldehyde-d3 is used as a synthetic building block for the creation of various organic compounds. Its deuterated nature provides unique properties that can be advantageous in specific chemical reactions, such as improved stability or altered reaction kinetics.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Hydroxy-4-methoxybenzaldehyde-d3 can be used as a starting material for the development of new drugs or drug candidates. Its deuterated form may offer benefits in terms of metabolic stability or reduced side effects when compared to non-deuterated analogs.
Used in Chemical Research:
3-Hydroxy-4-methoxybenzaldehyde-d3 is also employed in chemical research as a tool to study reaction mechanisms and to understand the effects of deuterium substitution on molecular properties and reactivity.
Used in Material Science:
In the field of material science, 3-Hydroxy-4-methoxybenzaldehyde-d3 can be utilized in the synthesis of novel materials with specific properties, such as improved thermal stability or enhanced chemical resistance, due to the presence of deuterium atoms.

Upstream product

• 865-50-9 iodomethane-d3 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 342611-04-5 4-benzaldehyde 

Relevant articles and documents

Biosynthesis of Benzylic Derivatives in the Fermentation Broth of the Edible Mushroom, Ischnoderma resinosum

Employing isotope incubation studies, the biosynthetic pathway leading to a series of benzylic derivatives was elucidated in the fermentation broth of the edible mushroom Ischnoderma resinosum (P. Karst). Twenty-six hydroxy- and methoxy- benzylic derivatives were screened by gas chromatography-mass spectrometry (GC-MS) of which 13 were detected in the culture media. Results from the isotope incubation studies showed the transformation of both benzyl alcohol and benzoic acid into benzaldehyde. Benzaldehyde was then converted into 4-methoxybenzaldehyde via hydroxylation and subsequent methylation of the 4-C position. The resulting 4-methoxybenzaldehyde was then hydroxylated in the 3-C position followed by methylation into 3,4-dimethoxybenzaldehyde. Based on these findings, a novel metabolic scheme for the biosynthesis of benzylic derivatives in I. resinosum was proposed. The knowledge of the biosynthetic pathway was utilized to produce 4-hydroxy-3-methoxybenzaldehyde (vanillin) from 4-hydroxy-3-methoxybenzoic acid (vanillic acid). This is the first report to elucidate the biosynthetic pathway of benzyl derivatives and production of vanillin from I. resinosum.

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