745073-18-1Relevant academic research and scientific papers
ENDOSOMOLYTIC AGENTS FOR GENE THERAPY
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Page/Page column 35, (2018/04/17)
Compounds of formula (I), wherein Ar is an aryl group optionally further substituted with one or more groups R3; A is a lipophilic, hydrophobic moiety; R1 is a phosphodiester, phosphotriester, thioether or amide group; X is an unsubs
Macrocyclic diacylglycerol-bis-lactones as conformationally constrained analogues of diacylglycerol-lactones. Interactions with protein kinase C
Kang, Ji-Hye,Kim, Su Yeon,Lee, Jeewoo,Marquez, Victor E.,Lewin, Nancy E.,Pearce, Larry V.,Blumberg, Peter M.
, p. 4000 - 4007 (2007/10/03)
A series of macrocyclic diacylglycerol (DAG)-bis-lactones were investigated as extreme conformationally constrained analogues of DAG-lactones in order to seek more potent protein kinase C (PKC) ligands with higher binding affinities and less lipophilicity
