74518-96-0Relevant academic research and scientific papers
Microwave-assisted solvent-free synthesis of (E)-stilbenes
Wang, Liu-Chang,Li, Jiang,Zhang, Xi-Quan,Gu, Hong-Mei,Li, Bao-Lin
experimental part, p. 231 - 234 (2012/09/08)
An efficient synthesis of a series of stilbenes is reported using 4-nitrotoluene and substituted arylaldehydes as starting materials in the presence of Cs2CO3 and polyethylene glycol under solvent-free microwave irradiation. Compared with conventional method, this strategy exhibited higher stereoselectivity, shorter reaction times and has a lower environmental impact.
Pd-catalyzed sequential C-C bond formation and cleavage: Evidence for an unexpected generation of arylpalladium(II) species
Youn, So Won,Kim, Byung Seok,Jagdale, Arun R.
supporting information; experimental part, p. 11308 - 11311 (2012/08/28)
A Pd(II)-catalyzed reaction engaging alkenyl β-keto esters is reported that leads to the formation of 1-naphthols and an unexpected generation of arylpalladium(II) species. Interception of the in situ generated arylpalladium(II) species in a Mizoroki-Heck reaction, together with additional mechanistic studies, provided strong evidence in support of the first aromatization-driven β-carbon elimination process. A single Pd catalyst served to promote a series of both C-C bond forming and cleavage events in an unprecedented manner.
Metabolic N-Hydroxylation. Use of Substituent Variation to Modulate the in Vitro Bioactivation of 4-Acetamidostilbenes
Hanna, Patrick E.,Gammans, Richard E.,Sehon, Russell D.,Lee, Man-Kil
, p. 1038 - 1044 (2007/10/02)
N-Hydroxylation is an obligate step in the bioactivation of carcinogenic aryl amides.Previous reports from this laboratory demonstrated that variation of the 4' substituent of trans-4-acetamidostilbene (1) has a marked effect on the rate of its in vitro m
