74518-99-3Relevant articles and documents
Metabolic N-Hydroxylation. Use of Substituent Variation to Modulate the in Vitro Bioactivation of 4-Acetamidostilbenes
Hanna, Patrick E.,Gammans, Richard E.,Sehon, Russell D.,Lee, Man-Kil
, p. 1038 - 1044 (2007/10/02)
N-Hydroxylation is an obligate step in the bioactivation of carcinogenic aryl amides.Previous reports from this laboratory demonstrated that variation of the 4' substituent of trans-4-acetamidostilbene (1) has a marked effect on the rate of its in vitro m