74530-80-6

Basic information

• Product Name: 4-Benzyliden-3-methyl-2-trifluormethyl-1,3-oxazolidin-5-on
• Synonyms: 4-Benzyliden-3-methyl-2-trifluormethyl-1,3-oxazolidin-5-on
• CAS NO: 74530-80-6
• Molecular Weight: 257.212
• Mol File: 74530-80-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Benzyliden-3-methyl-2-trifluormethyl-1,3-oxazolidin-5-on(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Benzyliden-3-methyl-2-trifluormethyl-1,3-oxazolidin-5-on(74530-80-6)
• EPA Substance Registry System: 4-Benzyliden-3-methyl-2-trifluormethyl-1,3-oxazolidin-5-on(74530-80-6)

Safety Data

• Hazardous Substances Data: 74530-80-6(Hazardous Substances Data)

Upstream product

• 2566-30-5 N-Methyl-L-phenylalanine 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 156-06-9 2-oxo-3-(phenyl)propionic acid 

Relevant articles and documents

Reactions of Amino Acids and Peptides, III. - Preparation of 1,3-Oxazolidin-5-one Derivatives from N-Methyl Amino Acids with Hexafluoroacetic Anhydride

N-Methyl amino acids react with hexafluoroacetic anhydride to give 1,3-oxazolidin-5-one derivatives in good yields.The structure of these products has been derived by 1H-NMR, mass and IR spectroscopy.Alkaline hydrolysis results in the formation of α-keto carboxylic acids.The reaction of 4-trifluoroacetylmethylene-1,3-oxazolidin-5-one derivatives with ammonia yields Δ3-pyrrolin-2-one derivatives, while methanol results in ring opening and formation of methyl esters of α,β-unsaturated N-methyl amino acids.