74533-11-2

Basic information

• Product Name: SODIUMALPHA-CHLOROPROPIONATE
• Synonyms: SODIUMALPHA-CHLOROPROPIONATE;L-ALPHA-CHLOROPROPIONICACIDSODIUMSALT
• CAS NO: 74533-11-2
• Molecular Formula: C₃H₄ClO₂*Na
• Molecular Weight: 0
• Mol File: 74533-11-2.mol

Chemical Properties

• Boiling Point: 189°C at 760 mmHg
• Flash Point: 68.1°C
• Appearance: /
• Vapor Pressure: 0.26mmHg at 25°C
• CAS DataBase Reference: SODIUMALPHA-CHLOROPROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: SODIUMALPHA-CHLOROPROPIONATE(74533-11-2)
• EPA Substance Registry System: SODIUMALPHA-CHLOROPROPIONATE(74533-11-2)

Safety Data

• Hazardous Substances Data: 74533-11-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C3H5ClO2.Na/c1-2(4)3(5)6;/h2H,1H3,(H,5,6);/q;+1/p-1/t2-;/m0./s1

Upstream product

• 29617-66-1 (S)-2-chloropropanoic acid 
• 56-41-7 L-alanin 

Downstream Products

• 94050-90-5 (R)-2-(4-hydroxyphenoxy)propionic acid 
• 1129-46-0 (R)-(+)-2-phenoxypropionic acid 
• 99967-54-1 2,2'-<1,4-Phenylenbis(oxy)><(2R,2'R)-bis(propionsaeure)> 
• 2862-03-5 Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(R)-1-carboxyethyl>-α-D-glucopyranoside 

Relevant articles and documents

Chemical synthesis method of (R)-2-phenoxypropionic acid

The invention discloses a chemical synthesis method of (R)-2-phenoxypropionic acid. The chemical synthesis method comprises the following steps: performing diazotization and chlorination on L-alanineserving as a starting material to obtain (S)-2-chloropro

Synthesis method of R-(+)-2-(4-hydroxyphenoxy) propionic acid

The invention discloses a synthesis method of R-(+)-2-(4-hydroxyphenoxy) propionic acid. The method comprises the following steps: (1), adding hydroquinone into a sodium hydroxide solution containingan organic solvent in batches, and performing reaction under in N2 atmosphere, so as to obtain p-hydroxy sodium phenate turbid liquid; (2), dissolving S-(-)-2-chloropropionic acid in an organic solvent, and slowly adding Na2CO3 solid in an ice-water bath condition to perform reaction, so as to obtain an S-(-)-2-sodium chloropropionic acid solution; (3), slowly dropwise adding the solution in the step (2) into the turbid liquid in the step (1), and performing reduced pressure distillation, dissolution and acidification, extraction and reduced pressure distillation on obtained reaction liquid, so as to obtain white solid, namely the R-(+)-2-(4-hydroxyphenoxy) propionic acid. The synthesis method has the advantages of simple synthesis route, mild reaction condition, high product yield, high product optical purity ee value, high recovery rate of hydroquinone, less produced three wastes and low energy consumption.

Synthesizing method of L-2-sodium chloropropionate

The invention discloses a synthesizing method of L-2-sodium chloropropionate.The synthesizing method comprises the steps that hydrochloric acid is directly sucked or pumped into a reaction kettle, and L-2-aminopropionic acid solids are put into the reaction kettle; the temperature is lowered to 0 DEG C or below through an ice bath, prepared sodium nitrite is added in batches, stirring is stopped after reacting is finished, and standing under heat preservation is performed for 2-3 hours; suction filtration is performed, L-2-chloropropionic acid filtrate obtained through suction filtration is contained in a separating funnel oscillator to be extracted, obtained extracting solutions are merged after layering under standing is performed, alkali liquid is added into the merged extracting solution for a neutralization reaction, layering under standing is performed, an obtained oil layer is dichloromethane solvent, and a water layer is an aqueous solution of L-2-sodium chloropropionate.According to the synthesizing method of L-2-sodium chloropropionate, the alkali liquid is directly added into the dichloromethane extracting solution of L-2-chloropropionic acid for neutralization, distilling is replaced with layering, the whole dichloromethane distilling and recycling process is omitted, and therefore not only is the efficiency greatly improved, but also energy consumption is greatly reduced.