Welcome to LookChem.com Sign In|Join Free
  • or
The chemical compound "1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-1-ol, 2-chloro-2,4,5,7,12b,12chexahydro-, (1S,2S,12bS,12cS)-" is a complex, polycyclic organic molecule with a unique structure. It features a phenanthridin-1-ol core, which is a type of phenanthridine derivative, with a dioxolo and pyrrolo ring fused to it. The compound is hexahydro, indicating the presence of six hydrogen atoms in a cyclic structure, and it has a 2-chloro substituent, which means a chlorine atom is attached at the 2-position. The stereochemistry of the compound is defined by the (1S,2S,12bS,12cS) configuration, which specifies the spatial arrangement of the atoms at these positions. 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]- phenanthridin-1-ol,2-chloro-2,4,5,7,12b,12chexahydro-,(1S,2S,12bS,12cS)- is likely to be found in specialized fields such as medicinal chemistry or organic synthesis, where its specific structure and properties could be of interest for potential applications.

74555-92-3

Post Buying Request

74555-92-3 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

74555-92-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 74555-92-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,5,5 and 5 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 74555-92:
(7*7)+(6*4)+(5*5)+(4*5)+(3*5)+(2*9)+(1*2)=153
153 % 10 = 3
So 74555-92-3 is a valid CAS Registry Number.

74555-92-3Upstream product

74555-92-3Relevant academic research and scientific papers

FURTHER EXPERIMENTS ON STRUCTURE-ACTIVITY RELATIONSHIPS AMONG THE LYCORINE ALKALOIDS

Evidente, Antonio,Arrigoni, Oreste,Liso, Rosalia,Calabrese, Giuseppe,Randazzo, Giacomino

, p. 2739 - 2744 (1986)

Key Word Index - Sternbergia lutea; Amaryllidaceae; ascorbate biosynthesis inhibition; phenanthridine alkaloids; lycorine; narciclasine; structure-activity relationships.Syhthetic lycorine analogues, five Amaryllidaceae alkaloids and narciclasine, all structurally related to lycorine, were tested for their ability to inhibit ascorbic acid biosynthesis in vivo.The highest potency observed was displayed by narciclasine followed by compounds having an aromatic C-ring.Derivatives modified at C-1 and/or C-2 were inactive, while the compound with a double bond between these positions is a weak inhibitor.Also lutessine and its deacetyl derivative having an α-methoxyl group bonded to C-4 of the D-ring appeared completely inactive.These results confirm that the presence of an appropriately substituted C-ring is a neccessary requirement for optimal 'responsetriggering' conctact between the lycorine derivatives and the specific receptor.Functional groups jutting out from the α-side of the molecule do not allow a good fit with the binding sites.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 74555-92-3