74571-27-0 Usage
Uses
Used in Organic Synthesis:
(2S,4S)-4-(Diphenylphosphino)-2-<(diphenylphosphino)-methyl>-N-phenylcarbamoylpyrrolidine is used as a chiral ligand in organic synthesis for its ability to facilitate asymmetric reactions, leading to the production of enantiomerically pure compounds. The presence of the diphenylphosphino groups enhances its coordination capabilities with metal catalysts, which is crucial for enantioselective transformations.
Used in Chemical Catalysis:
In the field of chemical catalysis, (2S,4S)-4-(Diphenylphosphino)-2-<(diphenylphosphino)-methyl>-N-phenylcarbamoylpyrrolidine is utilized as a catalyst support or modifier. Its phosphino groups can bind to metal centers, creating active sites for catalytic reactions. This can improve the efficiency and selectivity of various catalytic processes.
Used in Medicinal Chemistry:
(2S,4S)-4-(Diphenylphosphino)-2-<(diphenylphosphino)-methyl>-N-phenylcarbamoylpyrrolidine is employed as a building block or a molecular scaffold in medicinal chemistry. The carbamoyl and diphenylphosphino groups can be used to attach various pharmacophores or bioactive molecules, potentially leading to the development of new drugs with improved properties.
Further research and experimentation are necessary to fully understand the properties and potential uses of (2S,4S)-4-(Diphenylphosphino)-2-<(diphenylphosphino)-methyl>-N-phenylcarbamoylpyrrolidine, as its complex structure and functional groups offer a wide range of possibilities across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 74571-27-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,5,7 and 1 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 74571-27:
(7*7)+(6*4)+(5*5)+(4*7)+(3*1)+(2*2)+(1*7)=140
140 % 10 = 0
So 74571-27-0 is a valid CAS Registry Number.
74571-27-0Relevant academic research and scientific papers
Efficient preparation of optically active (S)-(-)-3-methyl-γ-butyrolactone by catalytic asymmetric hydrogenation using chiral N-substituted pyrrolidinebisphosphine rhodium complexes
Takeda,Tachinami,Hosokawa,Aburatani,Inoguchi,Achiwa
, p. 2706 - 2708 (2007/10/02)
(S)-(-)-2-Methyl succinamic acid, which is a good precursor of (S)-(-)-3-methyl-γ-butyrolactone, can be prepared by homogeneous asymmetric hydrogenation of 2-methylene succinamic acid catalyzed by (2S,4S)-N-substituted-4-(diphenylphosphino)-2-[(diphenylphosphino)-meth yl]pyrrolidine-rhodium complexes. Various N-substituted pyrrolidine-bisphosphines were synthesized to find the optimum ligand for this purpose and to compare the effects of the N-substituents.
N-carbamoyl-4-diphenylphosphino-2-diphenylphosphinomethylpyrrolidines(CAPP). Efficient new chiral ligands for asymmetric hydrogenation
Ojima, Iwao,Yoda, Noriko
, p. 1051 - 1054 (2007/10/02)
A series of N-(N′-substituted carbamoyl)-4-diphenylphosphino-2-diphenylphosphinomethylpyrrolidines (CAPP) was prepared, which exhibited excellent stereoselectivity in the asymmetric hydrogenation of α-acetamidocinnamic acid derivatives and itaconic acid as chiral ligand of the rhodium(I) catalyst.
