74575-17-0 Usage
General Description
3-Bromo-4-chloroquinoline is a chemical compound that belongs to the class of quinoline derivatives. It is a heterocyclic aromatic compound containing a five-membered ring with nitrogen as a heteroatom. This chemical is used in organic synthesis and pharmaceutical research as a building block for the synthesis of various bioactive compounds and drugs. It possesses a halogenated quinoline structure, which imparts distinct chemical and physical properties that are useful in drug design and discovery. The compound has the potential for various pharmacological activities and has been investigated for its antimalarial, antiviral, and anticancer properties.
Check Digit Verification of cas no
The CAS Registry Mumber 74575-17-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,5,7 and 5 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 74575-17:
(7*7)+(6*4)+(5*5)+(4*7)+(3*5)+(2*1)+(1*7)=150
150 % 10 = 0
So 74575-17-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H5BrClN/c10-7-5-12-8-4-2-1-3-6(8)9(7)11/h1-5H
74575-17-0Relevant articles and documents
A concise synthesis of indoloquinoline skeletons applying two consecutive Pd-catalyzed reactions
Bogányi, Borbála,Kámán, Judit
, p. 9512 - 9519 (2013/10/08)
The indoloquinoline alkaloids cryptolepine (1), neocryptolepine (2), isocryptolepine (3), and isoneocryptolepine (4) are important tools in traditional medicine. Now, their precursors 1a-4a were synthesized in two steps starting from the corresponding bromo-iodoquinolines. Our strategy is based on palladium-catalyzed reactions, applying regioselective Buchwald-Hartwig amination on 2,3- and 3,4-dihaloquinolines followed by an intramolecular Heck-type reaction. Both steps were carried out under microwave irradiation.
