745783-85-1 Usage
Uses
Used in Coatings Industry:
(S)-(+)-2-NONYL ISOCYANATE is used as a key component in the production of polyurethane coatings. Its application is due to its ability to contribute to the formation of durable, high-quality, and versatile coatings with excellent adhesion and resistance properties.
Used in Adhesives Industry:
In the adhesives industry, (S)-(+)-2-NONYL ISOCYANATE is utilized as a reactive monomer for the synthesis of polyurethane adhesives. Its use is attributed to the strong bonding capabilities and flexibility it provides to the adhesive formulations, making them suitable for various applications, including automotive, construction, and packaging sectors.
Check Digit Verification of cas no
The CAS Registry Mumber 745783-85-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,5,7,8 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 745783-85:
(8*7)+(7*4)+(6*5)+(5*7)+(4*8)+(3*3)+(2*8)+(1*5)=211
211 % 10 = 1
So 745783-85-1 is a valid CAS Registry Number.
745783-85-1Relevant academic research and scientific papers
Piperidine-containing histamine H3 receptor antagonists of the carbamate series: The alkyl derivatives
Lazewska,Kiec-Kononowicz,Elz,Pertz,Stark,Schunack
, p. 403 - 410 (2007/10/03)
A series of N-alkyl urethanes, potential histamine H3 receptor antagonists, was prepared. Carbamate derivatives were synthesized from appropriate isocyanates and N-piperidinoalkan-1-ols. The novel compounds were evaluated for histamine H3 receptor activity in vitro on the guinea pig ileum. Some selected compounds were tested in vivo after p.o. application to mice and in vitro for selectivity towards other histamine receptors (H 1, H2) in functional assays in the guinea pig. The most potent H3 receptor antagonist in vitro was compound 14 (pA 2 = 7.2). Compound 14 was equipotent at M3 receptors and lacked H3 receptor activity in vivo. Predictions of octanol-water partition coefficient (Pallas) and metabolic fate (MetabolExpert, METEOR) were used to explore potential reasons for this absence of in vivo activity.
