745783-85-1 Usage
General Description
(S)-(+)-2-Nonyl isocyanate is a chemical compound with the molecular formula C11H21NO. It is a colorless to pale yellow liquid that is commonly used in the production of polyurethane coatings and adhesives. (S)-(+)-2-NONYL ISOCYANATE is a type of isocyanate, which is known for its strong odor and irritating effects on the skin, eyes, and respiratory system. The (S)-(+)-2-Nonyl isomer is more commonly used compared to its (R)-(-)-2-Nonyl isomer counterpart due to its superior reactivity and stability. It is important to handle this chemical with caution and use appropriate personal protective equipment when working with it.
Check Digit Verification of cas no
The CAS Registry Mumber 745783-85-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,5,7,8 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 745783-85:
(8*7)+(7*4)+(6*5)+(5*7)+(4*8)+(3*3)+(2*8)+(1*5)=211
211 % 10 = 1
So 745783-85-1 is a valid CAS Registry Number.
745783-85-1Relevant articles and documents
Piperidine-containing histamine H3 receptor antagonists of the carbamate series: The alkyl derivatives
Lazewska,Kiec-Kononowicz,Elz,Pertz,Stark,Schunack
, p. 403 - 410 (2007/10/03)
A series of N-alkyl urethanes, potential histamine H3 receptor antagonists, was prepared. Carbamate derivatives were synthesized from appropriate isocyanates and N-piperidinoalkan-1-ols. The novel compounds were evaluated for histamine H3 receptor activity in vitro on the guinea pig ileum. Some selected compounds were tested in vivo after p.o. application to mice and in vitro for selectivity towards other histamine receptors (H 1, H2) in functional assays in the guinea pig. The most potent H3 receptor antagonist in vitro was compound 14 (pA 2 = 7.2). Compound 14 was equipotent at M3 receptors and lacked H3 receptor activity in vivo. Predictions of octanol-water partition coefficient (Pallas) and metabolic fate (MetabolExpert, METEOR) were used to explore potential reasons for this absence of in vivo activity.
