74583-40-7Relevant academic research and scientific papers
Furan ring opening-pyrrole ring closure. A simple route to 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-3-ones
Trushkov, Igor V.,Nevolina, Tatyana A.,Shcherbinin, Vitaly A.,Sorotskaya, Lyudmila N.,Butin, Alexander V.
, p. 3974 - 3976 (2013/07/25)
We report here an application of a furan ring opening-Paal-Knorr pyrrole synthesis sequence for the transformation of furfurylamines into 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-3-ones.
Expeditious synthesis of chiral 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazines
Bhowmik, Subhendu,Kumar, Anil K.S.,Batra, Sanjay
, p. 2251 - 2254 (2013/05/08)
An expeditious one-pot two-step synthesis of chiral 4-substituted-6-methyl- 1,2-dihydropyrrolo[1,2-a]pyrazin-3(4H)-ones via reaction between 5-methyl furfurylamine and N-Boc amino acids is described. LiAlH4-mediated reduction of 4-substituted-6-methyl-1,2-dihydropyrrolo[1,2-a]pyrazin-3(4H)-ones affords respective chiral 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazines in excellent yields.
Preparation of Bi- and Tricyclic Pyrroles
Stetter, Hermann,Lappe, Peter
, p. 703 - 714 (2007/10/02)
Phthalimidoalkane-1,4-diones smootly react with aromatic and aliphatic amines to give the substituted (phthalimidoalkyl)pyrroles 1-16.Hydrazinolysis of these compounds yields tricyclic 4H-pyrrolobenzodiazepines 17-23 and bicyclic pyrrolo1,2-c
