7459-54-3

Basic information

• Product Name: 6-oxoheptanamide
• CAS NO: 7459-54-3
• Molecular Weight: 143.186
• Mol File: 7459-54-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-oxoheptanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-oxoheptanamide(7459-54-3)
• EPA Substance Registry System: 6-oxoheptanamide(7459-54-3)

Safety Data

• Hazardous Substances Data: 7459-54-3(Hazardous Substances Data)

Upstream product

• 55917-06-1 1,2-dimethylhexahydro-2H-azepin-7-one 

Relevant articles and documents

Ruthenium Tetroxide Oxidation of N-Alkyllactams

Ruthenium tetroxide (RuO4) oxidation of N-alkyllactams proceeded regioselectively depending on the size of lactam ring, except for the seven-membered ring.Four- and eight-membered N-methyl- and N-ethyllactams were oxidized at the exocyclic α-carbon adjacent to nitrogen to produce the N-acyllactams and NH-lactams, while five- and six-membered lactams underwent endocyclic oxidation to yield the cyclic imides.Oxidation of seven-membered lactams yielded a mixture of products arising from both exocyclic and endocyclic oxidations.These regioselectivities were confirmed in the oxidation of substrates having a tertiary carbon at the oxidation position.Keywords---oxidation; ruthenium tetroxide oxidation; regioselective oxidation; hydroxylation; imide synthesis; N-alkyllactam; N-acyllactams; imide; ruthenium tetroxide; two-phase method