7460-90-4Relevant articles and documents
GPR120 RECEPTOR AGONISTS AND USES THEREOF
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Page/Page column 101, (2012/01/06)
GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.
Silanyl phenols and naphthols
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Page/Page column 6, (2008/06/13)
There are described silanyl phenols and naphthols of formula (1a) or (1b), wherein R1 is hydrogen; halogen; hydroxy; C1-C20alkyl; C3-C12cycloalkyl; C1-C20alkoxy; trifluoromethyl; pentafluoroethyl; mono- or di-C1-C5alkylamino; hydroxy-C1-C5alkyl; or phenyl, phenyl-C1C20alkyl, phenoxy, phenyl-C1-C20alkoxy, naphthyl or naphthyl-C1-C20alkyl each unsubstituted or substituted by C1-C5alkyl, C3-C12cycloalkyl, C1-C5alkoxy, C3-C12cycloalkoxy, halogen, oxo, carboxy, carboxy-C1-C7alkyl ester, carboxy-C3-C12cycloalkyl ester, cyano, trifluoromethyl, pentafluoroethyl, amino, N,N-mono- or di-C1-C20alkylamino or by nitro; R2, R3 and R4 are each independently of the others hydrogen; C1-C20alkyl; or C3-C12-Cycloalkyl; R5, R6 and R7 are each independently of the others C1-C20alkyl, C5-C10aryl, C1-C20alkoxy, phenyl-C1-C20alkyl, phenyl-C1-C20alkoxy, C2-C5alkenyl, —O—Si—(C1-C5alkyl)3; or O—Si—(C1-C5alkyl)2-O—Si(C1-C5alkyl)3 and n is 0 or 1. The compounds exhibit a pronounced activity against Gram positive and Gram negative bacteria, and also against yeasts and moulds.