74610-87-0

Upstream product

• 93250-16-9 2-(2,2-Dibromo-vinyl)-5-nitro-thiophene 
• 17163-24-5 2,3-dibromo-3-(5-nitro-2-thienyl)propionic acid 
• 74610-86-9 (Z)-2-bromo-1-(5-nitro-2-thienyl)ethylene 
• 294638-17-8 trimethyl((5-nitrothiophen-2-yl)ethynyl)silane 

Downstream Products

• 189190-61-2 Ru(CC-(5-nitro-2-thienyl))(PPh3)2(η(5)-C5H5) 

Relevant academic research and scientific papers

An efficient method for the production of terminal alkynes from 1,1-dibromo-1-alkenes and its application in the total synthesis of natural product dihydroxerulin

An efficient method of preparing various terminal alkynes from 1,1-dibromo-1-alkenes by using TBAF (tetra-n-butylammonium fluoride) as a base and triphenylphosphane as a reductant was developed. This method is strong base and low/high temperatures free, and can tolerate a broad range of substrates. These advantages were well demonstrated by the application of this method to the total synthesis of polyene natural product dihydroxerulin.

Mono(η5-cyclopentadienyl)metal(II) complexes with thienyl acetylide chromophores: Synthesis, electrochemical studies, and first hyperpolarizabilities

A series of mono(η5-cyclopentadienyl)metal-(II) complexes with nitro-substituted thienyl acetylide ligands of general formula [M(η5 -C5H5)(L)(C≡C{C4H2S}nNO2)] (M = Fe, L = K

Synthesis, characterization, and solid-state polymerization of cross-conjugated octatetraynes

Two series of cross-conjugated 1,3,5,7-octatetraynes (1a-1l and 6a-6d) have been synthesized. UV-vis spectroscopic analysis shows that pendent groups connected to the cross-conjugated skeleton have little effect on the λmax energies, irrespective of whether the groups are electron withdrawing or donating. A number of the isolated products readily give crystals suitable for X-ray crystallography, and the solid-state structural properties of five derivatives (1k, 1l, 6a, 6c, and 6d) have been examined by X-ray crystallographic analysis. Parallel packing of the polyynes in the solid state indicates that four of the five samples are potentially suitable for topochemical polymerization, based on solid-state packing parameters θ, R, and d. Attempts to effect a solid-state reaction have been explored through UV-vis and γ-ray irradiation as well as thermal heating. The course of these reactions was monitored by differential scanning calorimetry (DSC) analysis, as well as UV-vis and solid-state 13C NMR spectroscopy (for 1d, 1j, 1k, and 6d), which offered evidence of polymer formation from these reactions. Structural determination of the product(s), however, remains elusive.

5-NITRO-2-THIENYLVINYLATION. NUCLEOPHILIC SUBSTITUTION ON 2-(2-BROMOVINYL)-5-NITROTHIOPHENE, NEW ONE-STEP METHOD FOR PREPARATION OF NEW BIOLOGICALLY ACTIVE ETHYLENIC DERIVATIVES OF 5-NITRO-2-THIOPHENE

A facile method for preparing 2-(2-X-vinyl)-5-nitrothiophenes has been established by the reaction of (Z)-2-(2-bromovinyl)-5-nitrothiophene with O, S and N nucleophiles.