74625-86-8

Upstream product

• 117845-52-0 (E)-2-(3,4-Dimethoxy-phenyl)-3-morpholin-4-yl-1-(2-nitro-phenyl)-propenone 
• 5703-21-9 3,4-dimethoxyphenylacetaldehyde 
• 58697-62-4 N-[1-(3,4-dimethoxy-phenyl)-ethylidene]-N'-phenyl-hydrazine 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 59816-56-7 2-(3,4-dimethoxyphenyl)-1H-indole 
• 501699-23-6 2-(3,4-dimethoxyphenyl)-2,3-dihydro-1H-indole 
• 74599-00-1 2-(3,4-Dimethoxy-phenyl)-3-(2-nitro-phenyl)-3-oxo-propionaldehyde 
• 85636-79-9 2-(3,4-Dimethoxy-phenyl)-1-(2-nitro-phenyl)-ethanone 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 84569-66-4 4-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-morpholine 
• 74599-11-4 [3-(3,4-Dimethoxy-phenyl)-oxiranyl]-(2-nitro-phenyl)-methanone 
• 74599-25-0 (E)-3-(3,4-Dimethoxy-phenyl)-1-(2-nitro-phenyl)-propenone 

Relevant academic research and scientific papers

Oxygenation of 2,3-dihydroindoles

Isatogens (3-oxo-3H-indole 1-oxides) possess interesting biological properties and development of a general method to construct these derivatives has now been developed. Indolines (2,3-dihydroindoles) and isatogens have been prepared in an efficient route starting from indoles substituted in position 2. Reduction of the 2-substituted indoles was performed with tin and hydrochloric acid to give racemic indolines, which were converted to isatogens by 3-chloroperoxybenzoic acid (m-CPBA).

Enamines: Part V - Synthesis of Substituted Phenyl Benzyl Ketones and 2-Arylisatogens

Three different approaches of o/p-nitrophenyl benzyl ketones and their limitation in the synthesis of 2-arylisatogens are described.

Antitubercular Agents : Part III - Synthesis of Substituted 2-Arylisatogens

A number of 2-arylisatogens (VII) have been prepared starting from o-nitroacetophenones (I).Condensation of I with different aromatic aldehydes (II) gives the corresponding o-nitrochalkones (III) which on epoxidation followed by treatment with BF3-etherat